Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Special issue of Gut Microbes on Helicobacter pylori

19.11.2013
A special issue on Helicobacter pylori has been published by Landes Bioscience (Austin, TX USA). The articles contained in this special issue of the journal Gut Microbes have been authored by world-class investigators and provide new insights into the pathophysiology, diagnosis, prevention, and treatment of this microbe.

Helicobacter pylori is a gram-negative, microaerophilic bacterium found in the stomach. Identified in the early 1980s, it was shown to be present in patients with chronic gastritis and gastric ulcers, conditions that were not previously believed to have a microbial cause. It is also linked to the development of duodenal ulcers and stomach cancer.

However, in over 80% of carriers, H. pylori does not cause symptoms and it has been suggested that the bacterium may play an important role in the natural stomach ecology. H. pylori is the most common bacterial infection worldwide, with more than half of the world's population harboring the bacterium in the upper gastrointestinal tract. While incidence is decreasing in Western countries, H. pylori infection is highly prevalent in developing countries. In the absence of targeted antimicrobial therapy, colonization typically lasts for decades.

Dr Richard Peek from Vanderbilt-Ingram Cancer Center and Cancer Biology (Nashville, TN USA) has worked with the editorial team of Gut Microbes to organize this special issue on H. pylori. Papers in the issue discuss the role of childhood infection in the sequelae of H. pylori disease (Guillermo Perez-Perez), how glyco-conjugates promote virulence of H. pylori (M Stephen Trent), interplay of various H. pylori factors with host protein receptors (Steffen Backert), the role of chronic inflammation and oxidative stress in H. pylori induced gastric cancer (Keith T Wilson), diet, microbial virulence, and H. pylori induced gastric cancer (Timothy L Cover), consequences of H. pylori infection in children in developing countries (Jean E Crabtree), role of the gastrointestinal microbiome in H. pylori pathogenesis (James G Fox), biomarkers of H. pylori associated gastric cancer (Jay V Solnick), H. pylori therapies in light of evolving resistance (Francis Mégraud), benefits of H. pylori treatment in childhood (Karen J Goodman), vaccination against H. pylori (Steven J Czinn), and a study investigating the influence of H. pylori on hepatitis C virus-associated liver cancer.

In an accompanying editorial, Dr Peek highlights the importance of understanding the relationship between H. pylori infection and carcinogenesis. He writes, "Delineation of bacterial, host, and environmental mediators that augment gastric cancer risk has profound ramifications for both physicians and biomedical researchers, as such findings will not only focus prevention approaches that target H. pylori-infected human populations at increased risk for stomach cancer, but will also provide mechanistic insights into inflammatory carcinomas that develop beyond the gastric niche." The full issue is available at the following link: http://www.landesbioscience.com/journals/gutmicrobes/toc/volume/4/issue/6/

Published by Landes Bioscience since 2010, Gut Microbes is a multi-disciplinary journal dedicated to bringing together basic and clinical research on all apects of microorganisms populating the intestine. Established in 2002, Landes Bioscience is an Austin, Texas-based publisher of biology research journals and books. For more information on Landes Bioscience, please visit http://www.landesbioscience.com/.

Andrew Thompson | EurekAlert!
Further information:
http://www.landesbioscience.com

More articles from Life Sciences:

nachricht New photocatalyst speeds up the conversion of carbon dioxide into chemical resources
29.05.2017 | DGIST (Daegu Gyeongbuk Institute of Science and Technology)

nachricht Copper hydroxide nanoparticles provide protection against toxic oxygen radicals in cigarette smoke
29.05.2017 | Johannes Gutenberg-Universität Mainz

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Strathclyde-led research develops world's highest gain high-power laser amplifier

The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.

The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

New insights into the ancestors of all complex life

29.05.2017 | Earth Sciences

New photocatalyst speeds up the conversion of carbon dioxide into chemical resources

29.05.2017 | Life Sciences

NASA's SDO sees partial eclipse in space

29.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>