Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Simple Steps Prevent Life-Threatening Bloodstream Infections in Children

22.01.2010
Pediatric hospitals can significantly decrease the number of bloodstream infections from central venous catheters by following some low-tech rules: Insert the catheter correctly and, above all, keep everything squeaky clean after that.

Yearlong research led by Marlene Miller, M.D. Ms.C., of the Johns Hopkins Children’s Center with colleagues from other hospitals saw a 43 percent drop in the rate of bloodstream infections from catheters in 29 pediatric intensive care units (PICUs) that focused on careful placement and basic daily cleaning of the devices.

Results are to be published in the February issue of the journal Pediatrics.

Each year, 250,000 central line infections occur in the United States, researchers estimate, and up to one-fourth of patients die from them. Between 10 and 20 percent of children who get such infections die from them, researchers believe, and each infection carries a cost of $50, 000.

“If every single pediatric intensive care unit applies this approach rigorously and systematically, I’d be surprised if it didn’t translate into hundreds of lives and millions of dollars saved,” says Miller. Miller serves as vice president for quality transformation at the National Association of Children’s Hospitals and Related Institutions (NACHRI), which spearheaded the initiative.

A central venous catheter, or central line, is a tube inserted into a major blood vessel in the neck, chest or groin to serve as a temporary portal for injected medications and fluids, or blood sampling in patients who need them frequently. Because central lines also provide quick access in emergencies, children in the PICU often have them for weeks or longer. But if inserted incorrectly and, more importantly, mishandled after that, the central line can become a contaminated gateway for bacteria to enter directly into the patient’s bloodstream.

Therefore, investigators say, simple precautions like regularly changing the dressing covering the central line, changing the tubes and caps attached to it, cleaning the line before and after use, and rigorous hand washing before handling the line are essential to keeping bacteria away.

The new research also showed that while proper placement and daily care were both important in reducing catheter-related bloodstream infections, proper daily maintenance played the greatest role in preventing infections in children.

“Children, for example, may require more frequent blood draws through their catheter than adult patients so their central lines are handled more frequently on a day-to-day basis, which makes routine care for the device that much more critical in children than in adults,” Miller says.

The research further showed that medical staff compliance with day-to-day handling of central lines increased from 65 percent to 82 percent during the study period, suggesting that continuing education of medical staff and reminders to follow catheter protocol should be a mainstay in every PICU.

The research, launched as part of a nationwide effort to minimize preventable complications and deaths from this commonly used intravenous device, continues with more than 40 PICUs joining the initiative over the last two years. The effort continues today with more than 60 PICUs and is focused on further improving daily practices for central line handling.

Co-investigators include Michael Griswold, Ph.D., and Gayane Yenokyan, M.D. M.P.H. , of the Johns Hopkins Bloomberg School of Public Health; Mitchell Harris II, Ph.D., NACHRI; Charles Huskins, M.D., Mayo Clinic; Michele Moss, M.D., Arkansas Children’s Hospital; Tom Rice, M.D., Children’s Hospital of Wisconsin; Debra Ridling, R.N. , M.S., C.C.R.N., Children’s Hospital and Regional Medical Center, Seattle; Deborah Campbell, R.N., C. C.C.R.N., Kasair Children’s Hospital; Peter Margolis, M.D. Ph.D., Center for Child Health Quality; Richard Brilli, M.D., Nationwide Children’s Hospital.

Founded in 1912 as the children's hospital of the Johns Hopkins Medical Institutions, the Johns Hopkins Children's Center offers one of the most comprehensive pediatric medical programs in the country, treating more than 90,000 children each year. Hopkins Children’s is consistently ranked among the top children's hospitals in the nation. Hopkins Children’s is Maryland's largest children’s hospital and the only state-designated Trauma Service and Burn Unit for pediatric patients. It has recognized Centers of Excellence in dozens of pediatric subspecialties, including allergy, cardiology, cystic fibrosis, gastroenterology, nephrology, neurology, neurosurgery, oncology, pulmonary, and transplant. For more information, please visit www.hopkinschildrens.org

Ekaterina Pesheva | EurekAlert!
Further information:
http://www.hopkinschildrens.org
http://www.jhmi.edu

More articles from Life Sciences:

nachricht A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>