Dr Paul Schofield of the Department of Physiology Development and Neuroscience at the University of Cambridge chaired an influential meeting on this issue in Rome in May of this year, supported by the European Commission-funded CASIMIR project (www.casimir.org.uk).
CASIMIR is tasked to look at the factors inhibiting the free exchange of data and materials between investigators using the mouse as a model system to study human disease.
The meeting was attended by senior representatives of major international research sponsors, leading scientific journals, intellectual property and technology transfer specialists and sociologists. It endorsed the need for global coordination and effective policies to reduce barriers to the free exchange of data and materials between scientists to ensure the sharing of research results and materials to maximize research benefit, optimize the use of research sponsorship and more effectively manage and optimize the dissemination of biological research results through academic or commercial channels.
Significant consensus was achieved, and the results of this important meeting are published in Nature this week. Research on mice as models for human diseases is of major current international importance and is essential until better alternatives are found if the full societal benefits of the elucidation of the human genome are to be achieved. Better sharing of data and existing mice will reduce the need to generate new model organisms and avoid unnecessary duplication.
One of the key findings of this study is the negative impact of over-restrictive licensing by some Universities and research agencies of genetically engineered mice and embryonic stem cells - the outputs of this research - and the failure of researchers to efficiently share their research results and materials by depositing their mice and ES cells in the major public repositories now in place in Europe, North America, Japan and Australia.
The meeting set an agenda for community discussion - The Rome Agenda - also free to access online, which outlines guidelines to enable sharing of biomaterials under the least restrictive terms, avoiding restrictive material transfer agreements (MTAs) where possible. The meeting also recommended increased investment in public databases and mouse repositories to keep pace with the rapid acceleration of research in this area.
Dr Schofield said: "Sharing of data and biological resources in the post-genomic age has become crucial to the advancement of the biomedical sciences. The agreements reached in Rome will help to coordinate the development of policies and infrastructure in international science resulting in huge advantages to the research community and better value for money to the public agencies and charities who fund the majority of this research."
The Rome Agenda is intended to spark community discussion on this subject. Paul Schofield, Tania Bubela (University of Alberta, Edmonton, Canada) and other meeting participants will respond to reader comments in two online forums on Nature Network which will go live after the embargo has lifted: http://network.nature.com/groups/naturenewsandopinion/forum/topics/5433 http://network.nature.com/groups/naturenewsandopinion/forum/topics/5434
Notes to Editors:
1. The commentary piece "Post-publication sharing of data and tools" is scheduled for publication in the journal Nature on 09 September 2009.
2. Further recent discussions of some of these issues can be found on the Nature website: http://www.nature.com/news/2009/090603/full/459620a.html http://www.nature.com/nature/journal/v459/n7248/full/459752a.html
Dr. Paul Schofield | EurekAlert!
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Second research flight into zero gravity
21.10.2016 | Universität Zürich
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences