Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists Identify and Compare Yeast Genomes

24.06.2011
If you think yeast is most useful for beer and pizza crust, here’s something else to chew on: a team of U.S. researchers has identified and compared the genetic codes for all known species of yeasts closely related to bakers’ and brewers’ yeast.

This information, published in the Genetics Society of America’s new open-access journal, G3: Genes | Genomes | Genetics (http://www.g3journal.org), lays the foundation for future understanding of mutation and disease, as studies of yeasts often identify key genes and mechanisms of disease.

“We hope to learn to read the language of DNA and tell when mutations or differences will cause disease and when they will be advantageous,” said Chris Todd Hittinger, senior author of the work from the Department of Biochemistry and Molecular Genetics at the University of Colorado School of Medicine in Aurora, Colorado. “Providing a complete catalog of diversity among this group of species will allow us to quickly test which changes are responsible for which functions in the laboratory with a level of precision and efficiency not possible in other organisms.”

Using massively parallel next-generation DNA sequencing, the researchers determined the genome sequences, doubling the number of genes available for comparison, and identifying which genes changed in which species. They did this by segmenting each organism’s DNA into small pieces, and then computationally “reassembled” the pieces and compared them to the genome of S. cerevisiae (the species used to make beer, bread, wine, etc.) to identify similarities and differences. The researchers also genetically engineered several of the strains to make them amenable for experimentation. Results from this study will allow researchers to compare the genetics, molecular biology, and ecology of these species. Because yeast genomes and lifestyles are relatively simple, determining how diversity is encoded in their DNA is much easier than with more complex organisms, such as humans.

“The experimental resources described in this paper extend the value of yeasts for understanding biological processes,” said Brenda Andrews, Editor-in-Chief of G3: Genes | Genomes | Genetics, “and if they help us make better pizza crust and beer along the way, all the better.”

The Genetics Society of America established G3: Genes | Genomes |Genetics (http://www.g3journal.org) to meet the need for rapid review and publication of high-quality foundational research and experimental resources in genetics and genomics – an outlet unrestricted by subjective editorial criteria of perceived significance or predicted breadth of interest. Papers published in G3 describe useful, well-executed and lucidly interpreted genetic studies of all kinds. This new peer-reviewed, peer-edited, and fully open access journal meets crucial needs that are not met by current journals in this field.

Founded in 1931, the Genetics Society of America is the professional membership organization for geneticists and science educators. Its nearly 5,000 members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level.

Scannell et al. g3 June 2011 1:11-25; doi:10.1534/g3.111.000273
http://www.g3journal.org/content/1/1/11.full
The Awesome Power of Yeast Evolutionary Genetics: New Genome Sequences and Strain Resources for the Saccharomyces sensu stricto Genus

Tracey DePellegrin Connelly | Newswise Science News
Further information:
http://www.g3journal.org

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>