The set of 80,000 full-length human cDNA, which covers nearly the entire human genome, was made available on 15 March 2010 for general use through the RIKEN BioResource Center (BRC).
Initiated in 2004 on the heels of the first complete sequencing of the human genome, the GNP aims to clarify the structure of gene and protein–protein interactions toward applications in treatment and drug development.
By its completion in 2008, the project had succeeded in generating important scientific findings, producing vast amounts of experimental data in the process. To organize this data, the GNP created the Genome Network Platform, a visual interface enabling users to search genes, browse the genome, and analyze expression profiles.
It is through this platform that the 80,000 full-length human cDNA clones are being released. Two types of clones make up this new resource: a collection of 30,000 full-length human cDNA clones compiled by groups at The University of Tokyo and the RIKEN Omics Science Center, and 50,000 Gateway® entry clones reconstructed based on the cDNA clones. The Gateway® entry clones include clones made from cDNA created by the Research Association for Biotechnology under the New Energy and Industrial Technology Development Organization (NEDO) Full-length Human cDNA Sequencing Project. Researchers interested in obtaining the cDNA clones from either of these sets should visit the website of the Genome Network Platform (genomenetwork.nig.ac.jp), operated by the National Institute of Genetics, and place an order through the RIKEN BRC. Details on ordering cDNA clones can be found at the BRC’s DNA Bank website (www.brc.riken.jp/lab/dna/en/GNPcloneen.html).
Full-length cDNA clones offer researchers a powerful means to investigate the expression of messenger RNA, study proteins and especially protein function, and isolate specific genes. As one of the most important basic resources for genomic research, the provision of these new clones offers a valuable opportunity for researchers, promising key advances in treatment and drug discovery.
gro-pr | Research asia research news
'Lipid asymmetry' plays key role in activating immune cells
20.02.2018 | Biophysical Society
New printing technique uses cells and molecules to recreate biological structures
20.02.2018 | Queen Mary University of London
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
20.02.2018 | Life Sciences
20.02.2018 | Medical Engineering
20.02.2018 | Physics and Astronomy