Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Research Technology to Target Human Gut Bacteria

16.09.2010
The National Institutes of Health has awarded a three-year, $1.1 million grant to a team of scientists at the University of Chicago and Argonne National Laboratory to develop a technology for studying the link between human health and disease and the microorganisms that reside in or on the human body.

The grant is one of 14 awarded nationwide to research groups as part a $42 million expansion of the Human Microbiome Project. The human microbiome consists of beneficial and harmful microbes that include bacteria, viruses and fungi. The NIH launched the five-year, $157 million project in 2008 to serve as a research resource and to provide strategies for developing new therapies that manipulate the human microbiome to improve health.

Leading the UChicago-Argonne team will be Rustem Ismagilov, Professor in Chemistry. Joining him on the project are Eugene B. Chang, the Martin Boyer Professor of Medicine; Dionysios Antonopoulos, Assistant Professor of Medicine and biologist at Argonne, and Folker Meyer; associate director of Argonne’s Institute for Genomics and Systems Biology.

Historically, microbes have been studied in the laboratory as cultures of isolated species, but their growth is dependent upon a specific natural environment that is often difficult to duplicate. The NIH now seeks to develop techniques that can both increase the success rate for cultivating microbes and target cultivation efforts toward microbes of high biomedical interest.

The UChicago-Argonne team will use microfluidics to overcome the limitations of traditional cultivation and targeting methods by developing a single-cell confinement technology. Microfluidics is a means of precisely controlling the flow of liquids through channels thinner than a human hair.

The team will use sulfur-reducing bacteria from the human colon as the test system. These poorly understood bacteria are associated with ulcerative colitis and intra-abdominal infections, but the technology will generally apply to the identification and cultivation of all classes of microbes in the human gut microbiome.

Steve Koppes | Newswise Science News
Further information:
http://www.uchicago.edu

More articles from Life Sciences:

nachricht Modern genetic sequencing tools give clearer picture of how corals are related
17.08.2017 | University of Washington

nachricht The irresistible fragrance of dying vinegar flies
16.08.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Gold shines through properties of nano biosensors

17.08.2017 | Physics and Astronomy

Greenland ice flow likely to speed up: New data assert glaciers move over sediment, which gets more slippery as it gets wetter

17.08.2017 | Earth Sciences

Mars 2020 mission to use smart methods to seek signs of past life

17.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>