The grant is one of 14 awarded nationwide to research groups as part a $42 million expansion of the Human Microbiome Project. The human microbiome consists of beneficial and harmful microbes that include bacteria, viruses and fungi. The NIH launched the five-year, $157 million project in 2008 to serve as a research resource and to provide strategies for developing new therapies that manipulate the human microbiome to improve health.
Leading the UChicago-Argonne team will be Rustem Ismagilov, Professor in Chemistry. Joining him on the project are Eugene B. Chang, the Martin Boyer Professor of Medicine; Dionysios Antonopoulos, Assistant Professor of Medicine and biologist at Argonne, and Folker Meyer; associate director of Argonne’s Institute for Genomics and Systems Biology.
Historically, microbes have been studied in the laboratory as cultures of isolated species, but their growth is dependent upon a specific natural environment that is often difficult to duplicate. The NIH now seeks to develop techniques that can both increase the success rate for cultivating microbes and target cultivation efforts toward microbes of high biomedical interest.
The UChicago-Argonne team will use microfluidics to overcome the limitations of traditional cultivation and targeting methods by developing a single-cell confinement technology. Microfluidics is a means of precisely controlling the flow of liquids through channels thinner than a human hair.
The team will use sulfur-reducing bacteria from the human colon as the test system. These poorly understood bacteria are associated with ulcerative colitis and intra-abdominal infections, but the technology will generally apply to the identification and cultivation of all classes of microbes in the human gut microbiome.
Steve Koppes | Newswise Science News
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
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In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
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By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
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COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
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