Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Research paves way for new generation of fungicides

06.10.2014

Plants that come under attack from pathogens have an automatic immune response. Fungi get around this plant immunity by injecting proteins into the host plant cells. These 'effector proteins' enable the fungi to escape the plant's immune system and allow the fungal cells to enter the plant unrecognised.

Exeter scientists have now shown that signalling organelles, known as 'early endosomes' act as long distance messengers in the fungi. They travel rapidly along long tube-like cells between the plant-invading fungal cell tip and the fungal cell nucleus.


Effector proteins enable the fungi to escape the plant's immune system and allow the fungal cells to enter the plant unrecognized.

Credit: University of Exeter

This rapid communication between the point of invasion and the fungal cell nucleus enables the fungus to produce the effector proteins that help evade the plant's immune response from the moment the fungus enters the host tissue.

This signalling mechanism occurs very early in the fungal infection process, at a time when the fungi are most accessible to fungicide treatment. Disabling the process could result in a new generation of fungicides that are able to act before the fungus has damaged the plant.

Professor Gero Steinberg from the University of Exeter said: "Pathogenic fungi are a major threat to our food security – they can devastate crops and cost billions of pounds worth of damage. In fact, losses of wheat, rice, and maize to fungal pathogens, per year, are the same as the annual spend by US Department of Homeland Security – some 60 billion US dollars.

As fast growing microbes, fungi adapt rapidly to anti-fungal treatments and so we need to develop new fungicides all the time. Our research has led to a better understanding of the mechanisms by which the intruder attacks and overcomes the plant defence. In order to efficiently protect crops, we must better understand molecular mechanisms like these that occur in the very earliest stages of infection."

Speaking about the research, Deputy Vice Chancellor, Professor Nick Talbot said "The University of Exeter is committed to tackling fundamental research questions to help control plant diseases, which threaten our food supply. We have built a very strong team of researchers studying fungal biology and plant pathology. This exciting discovery by Prof Steinberg's group provides a new potential route to disease control."

###

The research was supported by the Biotechnology and Biological Sciences Research Council.

The paper, 'Long-distance endosome trafficking drives fungal effector production during plant infection', is published in the journal Nature Communications.

Jo Bowler | Eurek Alert!
Further information:
http://www.exeter.ac.uk

More articles from Life Sciences:

nachricht Are there sustainable solutions in dealing with dwindling phosphorus resources?
16.10.2017 | Leibniz-Institut für Nutzierbiologie (FBN)

nachricht Strange undertakings: ant queens bury dead to prevent disease
13.10.2017 | Institute of Science and Technology Austria

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

Im Focus: New nanomaterial can extract hydrogen fuel from seawater

Hybrid material converts more sunlight and can weather seawater's harsh conditions

It's possible to produce hydrogen to power fuel cells by extracting the gas from seawater, but the electricity required to do it makes the process costly. UCF...

Im Focus: Small collisions make big impact on Mercury's thin atmosphere

Mercury, our smallest planetary neighbor, has very little to call an atmosphere, but it does have a strange weather pattern: morning micro-meteor showers.

Recent modeling along with previously published results from NASA's MESSENGER spacecraft -- short for Mercury Surface, Space Environment, Geochemistry and...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

Conference Week RRR2017 on Renewable Resources from Wet and Rewetted Peatlands

28.09.2017 | Event News

 
Latest News

A single photon reveals quantum entanglement of 16 million atoms

16.10.2017 | Physics and Astronomy

The melting ice makes the sea around Greenland less saline

16.10.2017 | Earth Sciences

On the generation of solar spicules and Alfvenic waves

16.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>