University of Toronto scientists map entire yeast genome
Led by Corey Nislow, a U of T Assistant Professor with the Banting and Best Department of Medical Research and Department of Molecular Genetics, the team created a complete, three-dimensional map of the yeast genome. This information was fed into a computer to build a software program that can predict where nucleosomes should be. The program worked remarkably well, and its accuracy will only improve with more data.
“When control is lost, cells make inappropriate proteins or divide inappropriately, which is what happens in diseases like cancer,” says Nislow, whose team worked closely with U of T Professor Timothy Hughes on the project. “Knowing where nucleosomes are is the first step in identifying what is going on in a cell and what the cell plans to do next, so this initial research could have big implications down the road for early detection of certain diseases.”
Scientists can tell by the presence of nucleosomes which genes are actively being converted into protein, and this information can function as an important first clue to disease detection.
Media Contact
More Information:
http://www.utoronto.caAll latest news from the category: Life Sciences and Chemistry
Articles and reports from the Life Sciences and chemistry area deal with applied and basic research into modern biology, chemistry and human medicine.
Valuable information can be found on a range of life sciences fields including bacteriology, biochemistry, bionics, bioinformatics, biophysics, biotechnology, genetics, geobotany, human biology, marine biology, microbiology, molecular biology, cellular biology, zoology, bioinorganic chemistry, microchemistry and environmental chemistry.
Newest articles
Lighting up the future
New multidisciplinary research from the University of St Andrews could lead to more efficient televisions, computer screens and lighting. Researchers at the Organic Semiconductor Centre in the School of Physics and…
Researchers crack sugarcane’s complex genetic code
Sweet success: Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants….
Evolution of the most powerful ocean current on Earth
The Antarctic Circumpolar Current plays an important part in global overturning circulation, the exchange of heat and CO2 between the ocean and atmosphere, and the stability of Antarctica’s ice sheets….