Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers develop micro Petri dish for massively parallel growth and screening of micro-organisms

09.11.2007
Scientists of Top Institute Food & Nutrition, Wageningen University and Research Centre, NIZO food research and the MESA+ Institute for Nanotechnology in the Netherlands have developed a new technology that allows unprecedented miniaturisation of the growth of micro-organisms.

On a chip with the size of a postage stamp, more than one million cultures can be grown in parallel which opens up a wide range of uses from diagnosis of infection to the improvement of industrial bacteria. The corresponding paper ‘The micro Petri dish, a million-well chip for the culture and high-throughput screening of microorganisms’ has been published in Proceedings of the National Academy of Science (online Early Edition) on 7th November 2007.

A team of microbiologists and micro-engineering experts developed the chip that has the potential to meet the automation and miniaturisation needs of modern microbiology. The development of high-throughput bacterial screening methods has been slow in an era of advancements in fields like genomics and proteomics. The ‘micro Petri dish’ allows growth assays to catch up with other high-throughput technologies in the life sciences. ‘Besides that, the chip is readily manufactured, cheap and easy-to-use in a standard microbiology lab’ explain researchers Colin Ingham (WUR) and Johan van Hylckama Vlieg (NIZO).

The innovation is in the micro-engineering of a unique porous ceramic to create millions of wells that serve as growth areas for micro-organisms. The micron-scale wells of the chip can be regarded as an array of millions of “micro Petri dishes”, where bacteria or yeasts are efficiently supplied with nutrients from below through a porous membrane. By using this chip, assays for the detection and growth of micro-organisms will become faster and cheaper whilst it permits larger screening operations for improved industrial strains than have been possible to date.

TI Food and Nutrition (www.tifn.nl) is a unique public/private partnership that generates vision on scientific breakthroughs in food and nutrition, resulting in the development of innovative products and technologies that respond to consumer demands for safe, tasty and healthy foods. 'This project, a close collaboration between biotechnologists and nanotechnologists, is a good example of the trans-disciplinary approach we have developed', says Jan Sikkema, programme director at Top Institute Food and Nutrition.

Jac Niessen | alfa
Further information:
http://www.wur.nl

Further reports about: Micro Petri dish Screening develop micro-organisms

More articles from Life Sciences:

nachricht Fingerprint' technique spots frog populations at risk from pollution
27.03.2017 | Lancaster University

nachricht Parallel computation provides deeper insight into brain function
27.03.2017 | Okinawa Institute of Science and Technology (OIST) Graduate University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Northern oceans pumped CO2 into the atmosphere

27.03.2017 | Earth Sciences

Fingerprint' technique spots frog populations at risk from pollution

27.03.2017 | Life Sciences

Big data approach to predict protein structure

27.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>