Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Synchrotron Radiation Illuminates How Babies’ Protective Bubble Bursts

07.11.2007
Researchers at the University of Reading, School of Pharmacy have developed an important new technique to study one of the most common causes of premature birth and prenatal mortality. The findings are published in the November 7 issue of the online, open-access journal PLoS ONE.

Dr Che Connon, a Research Councils UK Fellow in Stem Cells and Nanomaterials, and his team used a powerful X-ray beam to examine tiny structures within the protective sac - amniotic membrane - which surrounds the developing baby.

This beam can resolve structures far smaller than a light or electron microscope. Furthermore, unlike other more intrusive forms of microscopy, X-ray investigation requires no processing of the tissue before examination, so can produce an accurate measurement of amniotic membrane structure in its normal state.

When the protective sac raptures during labour this is when the mother’s waters burst; if premature rupture occurs it can result in death or mental retardation of the child. Currently premature birth is increasing and 40% are attributed to the early rupture of amniotic membranes. Thus, a better understanding of the rupture process will lead to better treatment, earlier diagnosis and fewer premature deliveries

... more about:
»amniotic »premature »structure

Dr Connon, an expert in tissue structure, said: “This is of interest to the general public because amniotic membrane rupture is an important stage in the start of labour. More importantly early rupture of the amniotic membranes occurs in up to 20% of all pregnancies worldwide, and is the most common cause of preterm birth, leading to babies dying or having major problems such as cerebral palsy. The paper describes a new breakthrough in understanding the structure of amniotic membranes and how they rupture. Hopefully this will lead to therapies designed to prevent preterm membrane rupture as well.”

“Rupture of amniotic sac has been associated with a weakening of the tissue, but there is very little information available concerning the detailed mechanics of how this actually occurs.”

“We have now identified a regular cross-work arrangement of fibre forming molecules within the amniotic membrane which give the tissue its strength. Furthermore we have detected nanoscale alterations in the molecular arrangement within areas associated with amniotic membrane rupture. These results suggest, for the first time, that it is the loss of this molecular lattice like arrangement that governs the timing of membranes rupture.”

“Therefore, by controlling the amniotic membranes molecular arrangement we believe we can prevent premature rupture and delivery in the future.”

Andrew Hyde | alfa
Further information:
http://www.plosone.org/doi/pone.0001147

Further reports about: amniotic premature structure

More articles from Life Sciences:

nachricht The birth of a new protein
20.10.2017 | University of Arizona

nachricht Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Shallow soils promote savannas in South America

20.10.2017 | Earth Sciences

How Obesity Promotes Breast Cancer

20.10.2017 | Life Sciences

How the smallest bacterial pathogens outwit host immune defences by stealth mechanisms

20.10.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>