Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Novel insecticidal toxins from bacteria

05.09.2007
A light-emitting strain of bacteria and a nematode worm, which work together to prey on soil-dwelling insects, use insecticidal toxins to kill their insect hosts. Scientists speaking today (Wednesday 5 September 2007) at the Society for General Microbiology’s 161st Meeting are now investigating the potential role of these toxins in bacteria pathogenic to humans. The meeting is at the University of Edinburgh, UK, and runs from 3-6 September 2007.

Speaker Michelle Hares, of the University of Exeter, studies insect-killing nematode worms which have symbiotic bacteria living in their guts. When the worm encounters insect prey, it burrows into the insect’s body and regurgitates the bacteria. These bacteria, called Photorhabdus luminescens, then release toxins directly into the insect’s bloodstream, rapidly killing it. The insect’s flesh then provides food for the bacteria and in turn the bacteria are food for the nematode.

“Once inside an insect, caterpillar or larva, the bacteria release a mixture of toxins which kill the victim”, says Michelle Hares of the University of Exeter’s Cornwall Campus. “The toxins we identified are made up of three different proteins, and all three are needed to kill the insect”. The Cornwall based scientists also discovered that the same genes needed to make these protein toxins are found in the Yersinia pestis bacteria which caused the bubonic plague, and in Yersinia pseudotuberculosis which causes thousands of cases of gastroenteritis today.

When the toxic proteins from both these human pathogenic bacteria were fed to tobacco hornworm caterpillars they had no effect, but when the same proteins were put on living cells from humans both Yersinia bacteria strains killed the cells.

... more about:
»Yersinia »bacteria »insect »insecticidal »kill

“Our initial interest in this group of toxins, was centered around the hunt for novel insecticides, but our work now suggests they may also play an important role in the evolution of human and mammalian disease”, says Michelle Hares. “Our findings suggest that insecticidal toxin complexes have been adapted by the Yersinia family of bacteria to attack mammalian cells. We are therefore currently investigating exactly how the toxin complexes elicit their response and how they are involved in the evolution of pathogenic disease in Yersinia”.

Lucy Goodchild | EurekAlert!
Further information:
http://www.sgm.ac.uk

Further reports about: Yersinia bacteria insect insecticidal kill

More articles from Life Sciences:

nachricht Cryo-electron microscopy achieves unprecedented resolution using new computational methods
24.03.2017 | DOE/Lawrence Berkeley National Laboratory

nachricht How cheetahs stay fit and healthy
24.03.2017 | Forschungsverbund Berlin e.V.

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>