Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New link between estrogen and breast cancer

28.08.2007
The female sex hormone estrogen turns on a gene linked to breast cancer, according to new research by Brisbane scientists.

The cancer biology team from UQ's Diamantina Institute for Cancer, Immunology and Metabolic Medicine, believe their finding will help explain the link between breast cancer and high levels of estrogen.

“What we've shown is that the ability of estrogen to switch this gene on is important for the growth of breast cancer cells,” Diamantina cancer biology research leader Professor Tom Gonda said.

The gene they studied, known as MYB, is found in about 70 percent of all breast cancers and is one of several dozen genes called oncogenes that promote cancer growth.

... more about:
»Estrogen »MYB »breast cancer

“What's important in breast cancer is the ability of estrogen to turn on MYB rather than there being a mutation in the gene itself,” Professor Gonda said.

He said the next step was to take the results, which come from isolated cancer cells grown in the laboratory, and test them in laboratory mice that are a better model for human patients.

“We're trying to show directly that MYB can induce cancerous changes in normal breast cells.”

Professor Gonda and his colleagues at UQ worked with researchers in Melbourne, Adelaide and the United States and published their findings this month in the prestigious scientific journal Proceedings of the National Academy of Sciences of the USA.

He said a drug that blocks the action of MYB might be used to treat breast cancer in the future but he warned that would take many years of hard work.

Professor Gonda | EurekAlert!
Further information:
http://www.uq.edu.au

Further reports about: Estrogen MYB breast cancer

More articles from Life Sciences:

nachricht Scientists unlock ability to generate new sensory hair cells
22.02.2017 | Brigham and Women's Hospital

nachricht New insights into the information processing of motor neurons
22.02.2017 | Max Planck Florida Institute for Neuroscience

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Microhotplates for a smart gas sensor

22.02.2017 | Power and Electrical Engineering

Scientists unlock ability to generate new sensory hair cells

22.02.2017 | Life Sciences

Prediction: More gas-giants will be found orbiting Sun-like stars

22.02.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>