Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diverse Viruses Show Signs of Common Ancestry

28.03.2002



The viruses that cause diseases as varied as AIDS, hepatitis and West Nile Virus may actually have more in common than was previously thought, new research reveals. According to a study that will appear in the March issue of the journal Molecular Cell, three major groups of viruses use similar mechanisms to replicate their genetic information after they have infiltrated the cells of a host.

There are six broad classes of viruses, each thought to represent a major evolutionary lineage. Michael Schwartz, Jianbo Chen and colleagues at the University of Wisconsin, Madison studied the viral replication process and found that key features of the procedure run parallel in three of the six groups. Positive-strand RNA viruses, reverse transcribing viruses and double-stranded RNA viruses, they report, use similar basic mechanisms to replicate, despite differences in how the viruses move between host cells. The scientists determined that the three groups, which together comprise more than half of the world’s known virus families, all replicate their genome using messenger RNA and generate spherules to sequester them within newly infected cells. "This new virus-induced compartment, in which the virus genome is reserved and copied, shows surprising similarities across these different virus groups," notes study co-author Paul Ahlquist of the Howard Hughes Medical Institute at the University of Wisconsin, Madison.

Such fundamental similarities in replication among the viruses suggest they may have common evolutionary origins, the authors write. "These results have added considerably to our understanding of these viruses, and any new basic knowledge is useful in control," Ahlquist says. "If you know the machinery, you know where to throw the wrench to mess it up."


Sarah Graham | alphagalileo

More articles from Life Sciences:

nachricht Decoding the genome's cryptic language
27.02.2017 | University of California - San Diego

nachricht New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Safe glide at total engine failure with ELA-inside

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

New pop-up strategy inspired by cuts, not folds

27.02.2017 | Materials Sciences

Sandia uses confined nanoparticles to improve hydrogen storage materials performance

27.02.2017 | Interdisciplinary Research

Decoding the genome's cryptic language

27.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>