The investment, under the Translation Award programme, will help Nottingham-based RegenTec Ltd to develop commercial products in the rapidly-developing field of regenerative medicine. The company has perfected techniques which could greatly enhance the repair of bone defects and fractures.
RegenTec Ltd was created to build on the world-changing research carried out by scientists at The University of Nottingham, Britain’s ‘University of the Year’. With support from the East Midlands Development Agency, the company has invented a unique material that works with stem cells and biopharmaceuticals to stimulate the regeneration of tissue in patients.
When injected into the body the material forms a highly porous scaffold structure, which encourages new tissues to form.
The unique scaffold mechanism also assists the delivery of stem cells and drugs without compromising their effectiveness. This offers a substantial opportunity to deliver a cure to patients with bone, liver, heart or nerve tissue defects.
Professor Kevin Shakesheff, Chief Scientific Officer at RegenTec, and Director of The Centre for Biomolecular Sciences at The University of Nottingham, said: “The ability to inject these scaffold materials could significantly reduce the need for invasive surgery in tissue repair.
“It will mean that operation and rehabilitation times could come down significantly. After injection, the porous material we use gradually degrades, leaving behind only newly formed bone tissue.”
RegenTec has developed an extensive portfolio of patents and hopes that its injectable technology can reach clinics within three years. Its first product – Injectabone – will be used as a replacement for bone grafting, which can be beset by problems which include a short supply of host bone, chronic post-operative pain, and an increased risk of infection. Injectabone will be launched in the US and European markets for use by orthopaedic surgeons.
The material will then be adapted to help in treatment of many other diseases.
Dr Robin Quirk, Managing Director, said: “Regenerative medicine is a hugely exciting worldwide industry that promises to radically improve many aspects of clinical practice. We have a world-first technology that has a remarkable range of future uses.
“The Wellcome Trust Award is a substantial step forward in ensuring that the UK plays a major role in the commercial and clinical development of regenerative medicine.”
Dr Susan Huxtable, Director of Intellectual Property and Commercialisation at The University of Nottingham, said: “The Wellcome Trust Award is recognition of the hard work and creativity of a large team of scientists who have worked at the University of Nottingham and within Regentec over the past five years.
“They are pioneers in terms of their science, but also in ensuring that the expertise and knowledge honed in a research-intensive university can be translated into commercial enterprise, and make a dynamic contribution to well-being and economic growth. We have enjoyed a record year in attracting third party investment to our portfolio of spin-out companies.”
Emma Thorne | alfa
Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz
Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences