The investment, under the Translation Award programme, will help Nottingham-based RegenTec Ltd to develop commercial products in the rapidly-developing field of regenerative medicine. The company has perfected techniques which could greatly enhance the repair of bone defects and fractures.
RegenTec Ltd was created to build on the world-changing research carried out by scientists at The University of Nottingham, Britain’s ‘University of the Year’. With support from the East Midlands Development Agency, the company has invented a unique material that works with stem cells and biopharmaceuticals to stimulate the regeneration of tissue in patients.
When injected into the body the material forms a highly porous scaffold structure, which encourages new tissues to form.
The unique scaffold mechanism also assists the delivery of stem cells and drugs without compromising their effectiveness. This offers a substantial opportunity to deliver a cure to patients with bone, liver, heart or nerve tissue defects.
Professor Kevin Shakesheff, Chief Scientific Officer at RegenTec, and Director of The Centre for Biomolecular Sciences at The University of Nottingham, said: “The ability to inject these scaffold materials could significantly reduce the need for invasive surgery in tissue repair.
“It will mean that operation and rehabilitation times could come down significantly. After injection, the porous material we use gradually degrades, leaving behind only newly formed bone tissue.”
RegenTec has developed an extensive portfolio of patents and hopes that its injectable technology can reach clinics within three years. Its first product – Injectabone – will be used as a replacement for bone grafting, which can be beset by problems which include a short supply of host bone, chronic post-operative pain, and an increased risk of infection. Injectabone will be launched in the US and European markets for use by orthopaedic surgeons.
The material will then be adapted to help in treatment of many other diseases.
Dr Robin Quirk, Managing Director, said: “Regenerative medicine is a hugely exciting worldwide industry that promises to radically improve many aspects of clinical practice. We have a world-first technology that has a remarkable range of future uses.
“The Wellcome Trust Award is a substantial step forward in ensuring that the UK plays a major role in the commercial and clinical development of regenerative medicine.”
Dr Susan Huxtable, Director of Intellectual Property and Commercialisation at The University of Nottingham, said: “The Wellcome Trust Award is recognition of the hard work and creativity of a large team of scientists who have worked at the University of Nottingham and within Regentec over the past five years.
“They are pioneers in terms of their science, but also in ensuring that the expertise and knowledge honed in a research-intensive university can be translated into commercial enterprise, and make a dynamic contribution to well-being and economic growth. We have enjoyed a record year in attracting third party investment to our portfolio of spin-out companies.”
Emma Thorne | alfa
New method to rapidly map the 'social networks' of proteins
27.06.2017 | Salk Institute
X-ray experiments reveal two different types of water
27.06.2017 | Deutsches Elektronen-Synchrotron DESY
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...
19.06.2017 | Event News
13.06.2017 | Event News
13.06.2017 | Event News
27.06.2017 | Earth Sciences
27.06.2017 | Earth Sciences
27.06.2017 | Life Sciences