Scientists from the universities of Copenhagen and Århus, Denmark are once again at the cutting edge of biotechnology. This time with cloned pigs that have been genetically modified so that they may function as animal models for the notorious Alzheimer’s disease. In the US alone, 5 million people suffer from this human brain disorder and globally the number is set at approx. 24 million (source: Alzheimer's Disease International: http://www.alz.co.uk/ )
- In the light of the intense focus on medical research at the University of Copenhagen and the continuous expansion of the pharmaceutical industry in Denmark, the ability to produce transgenic pig models for human diseases is a major prerequisite for future progress in this area, says Professor Ingrid Brück Bøgh from the Department of Large Animal Sciences, University of Copenhagen.
- The upcoming birth of these transgenic pig models constitutes a fantastic success for us. It is also a demonstration of the excellent cross-disciplinary collaboration between the experts at both universities, she continues.
- We now have evidence that our system is very well suited for the task of making disease models for human medicine, says Professor Gábor Vajta from the Department of Genetics and Biotechnology, Faculty of Agricultural Sciences, University of Aarhus.
Associate Professor Arne Lund Jorgensen, Institute of Human Genetics, Aarhus University and his group have made the gene construct with the putative Alzheimer gene and inserted into the somatic cells. These somatic cells were used for the nuclear transfer experiments performed at the Faculty of Agricultural Sciences, Aarhus University.
Professor Ingrid Brück Bøgh | alfa
New method opens crystal clear views of biomolecules
11.02.2016 | Deutsches Elektronen-Synchrotron DESY
Scientists from MIPT gain insights into 'forbidden' chemistry
11.02.2016 | Moscow Institute of Physics and Technology
Today, plants and microorganisms are heavily used for the production of medicinal products. The production of biopharmaceuticals in plants, also referred to as “Molecular Pharming”, represents a continuously growing field of plant biotechnology. Preferred host organisms include yeast and crop plants, such as maize and potato – plants with high demands. With the help of a special algal strain, the research team of Prof. Ralph Bock at the Max Planck Institute of Molecular Plant Physiology in Potsdam strives to develop a more efficient and resource-saving system for the production of medicines and vaccines. They tested its practicality by synthesizing a component of a potential AIDS vaccine.
The use of plants and microorganisms to produce pharmaceuticals is nothing new. In 1982, bacteria were genetically modified to produce human insulin, a drug...
Atomic clock experts from the Physikalisch-Technische Bundesanstalt (PTB) are the first research group in the world to have built an optical single-ion clock which attains an accuracy which had only been predicted theoretically so far. Their optical ytterbium clock achieved a relative systematic measurement uncertainty of 3 E-18. The results have been published in the current issue of the scientific journal "Physical Review Letters".
Atomic clock experts from the Physikalisch-Technische Bundesanstalt (PTB) are the first research group in the world to have built an optical single-ion clock...
The University of Würzburg has two new space projects in the pipeline which are concerned with the observation of planets and autonomous fault correction aboard satellites. The German Federal Ministry of Economic Affairs and Energy funds the projects with around 1.6 million euros.
Detecting tornadoes that sweep across Mars. Discovering meteors that fall to Earth. Investigating strange lightning that flashes from Earth's atmosphere into...
Physicists from Saarland University and the ESPCI in Paris have shown how liquids on solid surfaces can be made to slide over the surface a bit like a bobsleigh on ice. The key is to apply a coating at the boundary between the liquid and the surface that induces the liquid to slip. This results in an increase in the average flow velocity of the liquid and its throughput. This was demonstrated by studying the behaviour of droplets on surfaces with different coatings as they evolved into the equilibrium state. The results could prove useful in optimizing industrial processes, such as the extrusion of plastics.
The study has been published in the respected academic journal PNAS (Proceedings of the National Academy of Sciences of the United States of America).
Exceeding critical temperature limits in the Southern Ocean may cause the collapse of ice sheets and a sharp rise in sea levels
A future warming of the Southern Ocean caused by rising greenhouse gas concentrations in the atmosphere may severely disrupt the stability of the West...
09.02.2016 | Event News
02.02.2016 | Event News
26.01.2016 | Event News
11.02.2016 | Life Sciences
11.02.2016 | Physics and Astronomy
11.02.2016 | Earth Sciences