Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Light Against Light

26.06.2007
A large group of the Puschino researchers from the Institutes of Theoretical and Experimental Biophysics (RAS), of Basic Problems of Biology (RAS), of Biophysics of Cell (RAS) and the Branch of Institute of Bio-Organic Chemistry (RAS) set out to protect cells from fatal consequences of ultra-violet radiation. The researchers determined that ultra-violet action suppressing cell division could be neutralized by simultaneous irradiation by the vermeil red light.

Experiments were based on mouse cell culture (fibroblasts). Irradiation by ultraviolet with wave-length of 365 nanometers in the 1.8 joule per cubic centimeter dose suppressed their division. As a source of the vermeil red light, the researchers did not use laser but applied a matrix with the Luxeon Star LEDs, their wave-length being 625 nanometers.

The influence of this irradiation on cells depends on the dose. When the dose makes 0.9 joule per cubic centimeter, the vermeil red light stimulated cell division, the irradiation effect remaining even 72 hours afterwards. The twofold and fourfold increased dose suppressed cell division. This effect is similar to the action that the helium-neon laser has on human cells: certain doses of it stimulate cell division, but further radiation intensity increase inhibits it.

Having determined the influence of each type of irradiation on mouse fibroplasts, the researchers set about studying their joint action. They chose the division suppressing dose of the vermeil red light. In case of consecutive irradiation by ultra-violet and vermeil red light or vice versa (first, by vermeil red light and then – by ultraviolet), cell division rate was lower than that in case of only ultra-violet irradiation and several times lower than that in the reference.

However, although simultaneous irradiation suppressed cell division, still it did so to a much lower extent than consecutive irradiation. This phenomenon means that under certain doses of ultra-violet and vermeil red light the latter protects cells from the negative ultra-violet action. It is well-known that the red light of 70 nanometer wave-length also possesses the same protective effect.

The researchers assume that the vermeil red light activates respiratory enzyme – terminal cytochrome-c-oxidase, which increases concentration of active forms of oxygen, and this increase, for its part, stimulates cell division. Nevertheless, cell division stimulation occurs in a very narrow dosage range. The researchers also emphasize that they did not use a low intensity radiation laser as a source of visible light, but applies ordinary LEDs which also have a rather narrow emission band but they are more affordable and economical.

The effect described by the Puschino researchers explains the effective action of light-converting materials, which transform part of the ultra-violet radiation into additional light in the 580 to 750-nanometer range. These materials are now starting to be applied in medicine. The sunlight cures patients with trophic ulcers, cutaneous wounds and burns. It contains the ulter-violet component, which, passing through the light-converting film, accelerates injured skin regeneration.

Nadezda Markina | alfa
Further information:
http://www.informnauka.ru

Further reports about: Irradiation LIGHT Nanometer Radiation Ras cell division ultra-violet vermeil

More articles from Life Sciences:

nachricht The balancing act: An enzyme that links endocytosis to membrane recycling
07.12.2016 | National Centre for Biological Sciences

nachricht Transforming plant cells from generalists to specialists
07.12.2016 | Duke University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

NTU scientists build new ultrasound device using 3-D printing technology

07.12.2016 | Health and Medicine

The balancing act: An enzyme that links endocytosis to membrane recycling

07.12.2016 | Life Sciences

How to turn white fat brown

07.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>