Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Analysis For A Drug Addict

15.06.2007
Specialists of the Institute of Physiologically Active Substances, Russian Academy of Sciences, and of the Moscow Narcological Clinical Hospital #17 have developed a technique called “Dianarc” that allows to discover drug addicts at the very early stage, when they take narcotics occasionally.

The technique is based on identification of the antibody level in saliva and blood. For invention of this technique, Professor Marina Myagkova was recognized the best inventor woman by the World Intellectual Property Organization at the International exhibition of inventions in Geneva in April this year and was awarded the golden medal of the World Intellectual Property Organization and a prize.

Drug addiction begins with occasional drug taking – once in 2 to 3 weeks or once in 1 to 2 months. But previously existing analysis techniques allowed to discover drug metabolites only within one or two days after the intake, therefore, they are practically unable to prove that an individual took drug a week ago. Clinical changes in the organism are usually not seen either at this stage, but when they become apparent, the disease has already been developed. That is why Russian specialists suggested to use immune-enzyme analysis methods (based on detection of narcotics specific antibodies) for early detection of drug addiction.

First, the researchers developed similar techniques for chronical drug addicts. They determined that with the individuals who are taking opiates, amphetamines or the ephedrine or hemp preparations (cannabinoids) on a regular basis, these narcotics antibodies level increases. Antibodies belong to the immunoglobulin proteins class. The researchers educed specific narcotics antibodies from the patients’ blood serum, determined their specificity and ability to binding and successfully applied immunological methods to medical practice for diagnostics of drug addiction latent forms.

... more about:
»Analysis »Antibodies »narcotics »technique

To develop a more sensitive method, the specialists used the blood serum and saliva of practically healthy people and those of drug addicts who had voluntarily came to the clinic. The majority of drug addicts used to take opiates, amphetamines and (or) cannabinoids. The time of their last drug taking made from two hours to three months.

It has turned out that in case of narcotics dependence development, the M and A immunoglobulin synthesis intensifies in the patient’s immune system. The A immunoglobulins are of special interest to physicians as antibodies based on them circulate in the blood for a long time; they enable to determine if an individual took drugs half a year ago and to identify what particular ones were taken. The blood serum analysis is more sensitive and informative than the saliva analysis.

The “Dianarc technique enables to detect 2 to 4 months later if an individual did take drugs, the technique’s reliability exceeding 95 percent. At the Geneva exhibition, the Russian researcher’s invention received the international recognition. The authors assume that the ‘Dianarc’ will be useful for clinical and forensic medical practice, as well as for staff selection to enforcement and guard entities, for issue of driver’s licenses and weapon permissions.

Nadezda Markina | alfa
Further information:
http://www.informnauka.ru

Further reports about: Analysis Antibodies narcotics technique

More articles from Life Sciences:

nachricht Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH

nachricht Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>