The technique is based on identification of the antibody level in saliva and blood. For invention of this technique, Professor Marina Myagkova was recognized the best inventor woman by the World Intellectual Property Organization at the International exhibition of inventions in Geneva in April this year and was awarded the golden medal of the World Intellectual Property Organization and a prize.
Drug addiction begins with occasional drug taking – once in 2 to 3 weeks or once in 1 to 2 months. But previously existing analysis techniques allowed to discover drug metabolites only within one or two days after the intake, therefore, they are practically unable to prove that an individual took drug a week ago. Clinical changes in the organism are usually not seen either at this stage, but when they become apparent, the disease has already been developed. That is why Russian specialists suggested to use immune-enzyme analysis methods (based on detection of narcotics specific antibodies) for early detection of drug addiction.
First, the researchers developed similar techniques for chronical drug addicts. They determined that with the individuals who are taking opiates, amphetamines or the ephedrine or hemp preparations (cannabinoids) on a regular basis, these narcotics antibodies level increases. Antibodies belong to the immunoglobulin proteins class. The researchers educed specific narcotics antibodies from the patients’ blood serum, determined their specificity and ability to binding and successfully applied immunological methods to medical practice for diagnostics of drug addiction latent forms.
To develop a more sensitive method, the specialists used the blood serum and saliva of practically healthy people and those of drug addicts who had voluntarily came to the clinic. The majority of drug addicts used to take opiates, amphetamines and (or) cannabinoids. The time of their last drug taking made from two hours to three months.
It has turned out that in case of narcotics dependence development, the M and A immunoglobulin synthesis intensifies in the patient’s immune system. The A immunoglobulins are of special interest to physicians as antibodies based on them circulate in the blood for a long time; they enable to determine if an individual took drugs half a year ago and to identify what particular ones were taken. The blood serum analysis is more sensitive and informative than the saliva analysis.
The “Dianarc technique enables to detect 2 to 4 months later if an individual did take drugs, the technique’s reliability exceeding 95 percent. At the Geneva exhibition, the Russian researcher’s invention received the international recognition. The authors assume that the ‘Dianarc’ will be useful for clinical and forensic medical practice, as well as for staff selection to enforcement and guard entities, for issue of driver’s licenses and weapon permissions.
Nadezda Markina | alfa
More genes are active in high-performance maize
19.01.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
How plants see light
19.01.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
19.01.2018 | Materials Sciences
19.01.2018 | Health and Medicine
19.01.2018 | Physics and Astronomy