Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A first: Hebrew University scientist observes brain cell development in ‘real time’

24.05.2007
For the first time anywhere, a researcher at the Hebrew University of Jerusalem has succeeded in observing in vivo the generation of neurons in the brain of a mammal.

Dr. Adi Mizrahi of the Department of Neurobiology at the Alexander Silberman Institute of Life Sciences at the Hebrew University, used mouse models to study how neurons, or nerve cells, develop from an undifferentiated cellular sphere into a rich and complex cell. This has great significance for the future of brain research, said Dr. Mizrahi, since “the structural and functional complexity of nerve cells remains one of the biggest mysteries of neuroscience, and we now have a model to study this complexity directly.”

The results of Dr. Mizrahi’s groundbreaking work appeared in the online edition of Nature Neuroscience.

Using special microscopic imaging techniques, combined with virus gene technology, Dr. Mizrahi was able to develop an experimental model to study development of neural dendrites in vivo. The dendrites are the string-like extensions of the neuron that spread out to reach other neurons and serve as the points of communication between the neurons.

... more about:
»Development »Mizrahi »Neuron

The model employed by Dr. Mizrahi in his research was the newborn neuron population which develops into the olfactory bulb of adult mice, providing them with a sense of smell. The development and maintenance of newborn neurons in this area was assessed by time-lapse imaging over several days at different stages of development. Mizrahi revealed that dendritic formation is highly dynamic. Moreover, once incorporated into the network, adult-born neurons in the study also remained dynamic and capable of continuous change.

This method provides a mechanism for observing, for the first time in a mammal, how a neuron develops into a rich and complex cell and how, once developed, neurons are maintained in the highly active and changing environment of the brain.

As for further research that some day could lead to significant breakthroughs in treatment of neural disorders, Dr. Mizrahi noted that “there are only a few small areas in the brain which are capable of neurogenesis, and they hide secrets we want to reveal.”

Jerry Barach | alfa
Further information:
http://www.huji.ac.il

Further reports about: Development Mizrahi Neuron

More articles from Life Sciences:

nachricht Cryo-electron microscopy achieves unprecedented resolution using new computational methods
24.03.2017 | DOE/Lawrence Berkeley National Laboratory

nachricht How cheetahs stay fit and healthy
24.03.2017 | Forschungsverbund Berlin e.V.

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>