The degree is the first of its kind in the country, fulfilling a need to provide graduates with skills in the chemistry and biology of cancer, and direct experience of some of the very latest research in the field.
The course will cover new approaches to cancer diagnosis and treatment and involve the design and synthesis of small molecule cancer drugs, equipping graduates for employment in the pharmaceutical industry and in academia.
The pioneering degree has been developed by Dr. Paul Jenkins from the Department of Chemistry, who has research expertise in the development of chemotherapeutic drugs.
He said “I think that this unique course will equip graduates to take part in the exciting and rewarding field of anti-cancer drug development. It will explain the biological pathways involved in cancer and how to design non-toxic small molecules to intervene specifically in these pathways to produce the next generation of cancer drugs.”
The main issue with cancer chemotherapy at the moment is that it is based on selective toxicity of the cancer drug for the tumour cells. This selectivity is never perfect and the treatments have considerable side effects.
One of the newest cancer drugs is Gleevec which is a specific non toxic inhibitor of a key protein in a cancer control pathway. Future developments will involve drugs of this type.
Leicester is a national centre for clinical research in the field of cancer. The Chemistry Department is conducting research funded by CRUK to develop non-toxic inhibitors of a key check-point enzyme in the cell division process.
In cancer cells, growth is very rapid and one way to combat this is to stop cells dividing by specific inhibition of the enzymes that control the cell cycle. “Our results have been encouraging” said Dr. Jenkins, “and two of our researchers will present results at a medicinal chemistry conference in Lille later this year.”
The degree is aimed at graduates in chemistry or a related discipline and non-graduates with appropriate experience. Cancer Research UK has supplied three bursaries covering fees and stipend for UK and EEA students taking the MSc in Cancer Chemistry.
Ather Mirza | alfa
Unique genome architectures after fertilisation in single-cell embryos
30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH
Transport of molecular motors into cilia
28.03.2017 | Aarhus University
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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30.03.2017 | Health and Medicine
30.03.2017 | Health and Medicine
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