Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Food cue-related brain activity linked to obesity?

26.04.2007
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests.

It’s well known that food-associated cues, such as advertising, can influence food intake. But the underlying neurobiology is far from clear. Craig A. Schiltz and colleagues from the University of Wisconsin Madison School of Medicine and Public Health, USA, created an experimental set up that allowed them to study patterns of gene expression linked to this motivational state - rats conditioned to expect a chocolate-flavoured treat in a particular environment, were subsequently denied their reward.

The research, conducted in the laboratory of Ann E. Kelly showed that expression of a handful of immediate early genes was increased in cortical, striatal, thalamic and hypothalamic brain regions. Food-related cues triggered dramatic changes in the functional connectivity of circuits involved in adaptive behaviour. For example, increased connectivity was seen between the cortex and two other regions - the amygdala and the striatum. Within the latter, there was a shift in activity from the outer shell to the inner core of the nucleus accumbens and an increased expression of the opioid-encoding proenkephalin gene.

... more about:
»Brain »activity »linked

Taken together, these results suggest that food-associated cues have a powerful influence on neuronal activity and gene expression in brain areas mediating complicated functions such as cognition and emotion, and more basic abilities such as arousal and energy balance. The pattern of activation differs from that elicited by neutral cues, and may well contribute to a conditioned motivational state that can lead to excessive food intake.

Press Officer | alfa
Further information:
http://www.biomedcentral.com/bmcbiol/

Further reports about: Brain activity linked

More articles from Life Sciences:

nachricht Sensing Neuronal Activity With Light
19.09.2014 | California Institute of Technology

nachricht No sedative necessary: Scientists discover new “sleep node” in the brain
19.09.2014 | University at Buffalo

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

"Start-ups and spin-offs funding – Public and private policies", 14th October 2014

12.09.2014 | Event News

BALTIC 2014: Baltic Sea Geologists meet in Warnemünde

03.09.2014 | Event News

IT security in the digital society

27.08.2014 | Event News

 
Latest News

No sedative necessary: Scientists discover new “sleep node” in the brain

19.09.2014 | Life Sciences

Sensing Neuronal Activity With Light

19.09.2014 | Life Sciences

Miranda: An Icy Moon Deformed by Tidal Heating

19.09.2014 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>