Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Food cue-related brain activity linked to obesity?

26.04.2007
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests.

It’s well known that food-associated cues, such as advertising, can influence food intake. But the underlying neurobiology is far from clear. Craig A. Schiltz and colleagues from the University of Wisconsin Madison School of Medicine and Public Health, USA, created an experimental set up that allowed them to study patterns of gene expression linked to this motivational state - rats conditioned to expect a chocolate-flavoured treat in a particular environment, were subsequently denied their reward.

The research, conducted in the laboratory of Ann E. Kelly showed that expression of a handful of immediate early genes was increased in cortical, striatal, thalamic and hypothalamic brain regions. Food-related cues triggered dramatic changes in the functional connectivity of circuits involved in adaptive behaviour. For example, increased connectivity was seen between the cortex and two other regions - the amygdala and the striatum. Within the latter, there was a shift in activity from the outer shell to the inner core of the nucleus accumbens and an increased expression of the opioid-encoding proenkephalin gene.

... more about:
»Brain »activity »linked

Taken together, these results suggest that food-associated cues have a powerful influence on neuronal activity and gene expression in brain areas mediating complicated functions such as cognition and emotion, and more basic abilities such as arousal and energy balance. The pattern of activation differs from that elicited by neutral cues, and may well contribute to a conditioned motivational state that can lead to excessive food intake.

Press Officer | alfa
Further information:
http://www.biomedcentral.com/bmcbiol/

Further reports about: Brain activity linked

More articles from Life Sciences:

nachricht Biomarker in an aggressive breast cancer is identified
20.08.2014 | Northwestern University

nachricht Zombie ant fungi manipulate hosts to die on the 'doorstep' of the colony
19.08.2014 | Penn State

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

5th Technical Conference "Subsoil Analysis, Ground Improvement and Wind Turbine Foundations"

13.08.2014 | Event News

Consumer Research - ICCR 2014

07.08.2014 | Event News

Counting down to FEBS-EMBO 2014 in Paris, France

29.07.2014 | Event News

 
Latest News

New Tool Makes Online Personal Data More Transparent

20.08.2014 | Information Technology

Antibacterial soap exposes health workers to high triclosan levels

20.08.2014 | Studies and Analyses

Promising Ferroelectric Materials Suffer From Unexpected Electric Polarizations

20.08.2014 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>