Scientists in the Greene Infectious Disease Laboratory of the Columbia University Mailman School of Public Health and colleagues in the Victorian Infectious Diseases Reference Laboratory in Melbourne, Australia and 454 Life Sciences have discovered a new virus that was responsible for the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia.
The previously unknown virus, which is related to lymphocytic choreomeningitis virus (LCMV), was found using rapid sequencing technology established by 454 Life Sciences and bioinformatics algorithms developed in the Greene Laboratory with support from the National Institute of Allergy and Infectious Diseases. Known strains of LCMV have been implicated in a small number of cases of disease transmission by organ transplantation, however, the newly discovered virus is sufficiently different that it could not be detected using existing screening methods.
Over 30,000 organ transplants are performed in the U.S. each year. Knowledge of the genetic sequence of this virus will enable improvements in screening that will enhance the safety of transplantation.
Ian Lipkin, MD, director of the Greene Laboratory and Principal Investigator of the Northeast Biodefense Center, emphasized the importance of academic, public health, and industrial partnership in this work. "This was a team effort. Drs. Mike Catton and Julian Druce at the Victorian Infectious Disease Reference Laboratory reached out to us after a comprehensive state-of-the-art investigation failed to turn up leads," stated Dr. Lipkin. "We succeeded in identifying the virus responsible for the deaths by building on their work and utilizing new tools for pathogen surveillance and discovery developed in the Greene Laboratory and 454 Life Sciences."
Randee Sacks Levine | EurekAlert!
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Second research flight into zero gravity
21.10.2016 | Universität Zürich
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences