January 2007 marked the beginning of the second funding period of HepatoSys*, the Systems Biology Competence Network initiated by the German Federal Ministry of Education and Research (BMBF). The long-term objective of this project is to generate mathematical models capable of reconstructing physiological processes of liver cells “in silico”. The meaning of this to researchers in Systems Biology is the development of computer-based models on the basis of experimental data.
In the first funding period, scientists focused on developing the interdisciplinary network groups. Within Germany, they connected more than 30 working teams. The working methods had to be standardized and are now accessible to all members in the form of standardized protocols. In addition to that, the HepatoSys members working either in theoretical or biological research, draws together on a data management system tailored to their special needs. Thus, every researcher has easy access to all data and models developed and compiled within the network, a valuable source of new insights and synergies.
As the organizer of the Conference for Systems Biology of Mamallian Cells (SBMC), HepatoSys first attracted international attention in 2006. More than 300 participants from 16 countries had the opportunity to listen to talks of experts in Systems Biology and to learn about promising first research results of the competence network for liver cells. Subsequently, the Federal Ministry of Education and Research decided to budget 22 million Euros to fund the initiative for another three years.
Prof. Jens Timmer, physicist at the University of Freiburg, Germany, and scientific speaker of HepatoSys, is pleased that the initiative has been extended: “Now we have all the structures available which are essential for interdisciplinary collaboration in Systems Biology. In the coming three years, research will be the centre of attention. We are looking forward to this task and hope for early insights regarding the model system liver cell.” From the beginning, industry was also very interested in those research results. Actually commercial partners will contribute with about 1.5 million Euro to HepatoSys. Next to innovative developments in fighting cancer groundbreaking results in liver metabolism are expected.
* Word formation consisting of Hepatocyte – liver cell – and Systems Biology
Ute Heisner | alfa
Making fuel out of thick air
08.12.2017 | DOE/Argonne National Laboratory
‘Spying’ on the hidden geometry of complex networks through machine intelligence
08.12.2017 | Technische Universität Dresden
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
Physicists in the Laboratory for Attosecond Physics (run jointly by LMU Munich and the Max Planck Institute for Quantum Optics) have developed an attosecond electron microscope that allows them to visualize the dispersion of light in time and space, and observe the motions of electrons in atoms.
The most basic of all physical interactions in nature is that between light and matter. This interaction takes place in attosecond times (i.e. billionths of a...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
11.12.2017 | Physics and Astronomy
11.12.2017 | Earth Sciences
11.12.2017 | Information Technology