Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Polymers show promise for gene delivery, tissue scaffolds, other biomedical applications

28.03.2007
Virginia Tech polymer scientists have developed a new family of gene vectors – novel polymers that can ferry genetic material across the cell membrane so that it can be incorporated into the machinery of the cell.

Representing Virginia Tech faculty members and students from engineering, chemistry, and veterinary medicine, Chemistry Professor Tim Long will give an invited lecture at the 233rd National Meeting of the American Chemical Society in Chicago March 25-29.

The presentation will be an overview of novel polymers developed by Virginia Tech researchers for biomedical applications, with an emphasis on gene delivery and tissue scaffolds. “Both of these emerging technologies are enabled with fundamental advances in polymer chemistry,” Long said.

“Synthetic macromolecules can be easily modified to contain a variety of functional elements capable of interacting with biological systems,” he said. “Initial studies have found macromolecular topology to be a significant parameter in the delivery of DNA into cells.”

... more about:
»Biomedical »Polymer »scaffolds »vectors

In the cell, the new DNA initiates the manufacture of therapeutic proteins, such as might be needed to treat a genetic disease where an enzyme or protein is not produced naturally. The Virginia Tech vectors presently being tested in cell cultures are proving to be superior to surfactant benchmarks and offer reduced toxicity to viral vectors, Long said.

Meanwhile, scientists at Virginia Tech have developed a single-step process for creating fibrous mats from a small organic molecule – a new nanoscale, biocompatible material (Jan. 20, 2006, Science, "Phospholipid Nonwoven Electrospun Membranes," by Matthew G. McKee, John M. Layman, Matthew P. Cashion, and. Long, all at Virginia Tech.).

Since last year, they have improved the durability of the phospholipids through novel photochemistry during electrospinning and have begun to impregnate the porous mats with cells that will initiate tissue regeneration.

Susan Trulove | EurekAlert!
Further information:
http://www.vt.edu

Further reports about: Biomedical Polymer scaffolds vectors

More articles from Life Sciences:

nachricht Could this protein protect people against coronary artery disease?
17.11.2017 | University of North Carolina Health Care

nachricht Microbial resident enables beetles to feed on a leafy diet
17.11.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>