Representing Virginia Tech faculty members and students from engineering, chemistry, and veterinary medicine, Chemistry Professor Tim Long will give an invited lecture at the 233rd National Meeting of the American Chemical Society in Chicago March 25-29.
The presentation will be an overview of novel polymers developed by Virginia Tech researchers for biomedical applications, with an emphasis on gene delivery and tissue scaffolds. “Both of these emerging technologies are enabled with fundamental advances in polymer chemistry,” Long said.
“Synthetic macromolecules can be easily modified to contain a variety of functional elements capable of interacting with biological systems,” he said. “Initial studies have found macromolecular topology to be a significant parameter in the delivery of DNA into cells.”
In the cell, the new DNA initiates the manufacture of therapeutic proteins, such as might be needed to treat a genetic disease where an enzyme or protein is not produced naturally. The Virginia Tech vectors presently being tested in cell cultures are proving to be superior to surfactant benchmarks and offer reduced toxicity to viral vectors, Long said.
Meanwhile, scientists at Virginia Tech have developed a single-step process for creating fibrous mats from a small organic molecule – a new nanoscale, biocompatible material (Jan. 20, 2006, Science, "Phospholipid Nonwoven Electrospun Membranes," by Matthew G. McKee, John M. Layman, Matthew P. Cashion, and. Long, all at Virginia Tech.).
Since last year, they have improved the durability of the phospholipids through novel photochemistry during electrospinning and have begun to impregnate the porous mats with cells that will initiate tissue regeneration.
Susan Trulove | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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