Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New discovery about fatty tissue that burns fat

07.03.2007
In an article now being published in the leading American journal PNAS, a research team led by Barbara Cannon and Jan Nedergaard at the Wenner-Gren Institute, Stockholm University in Sweden, together with British and American scientists, have managed to show for the first time that the cells that become the so-called brown or white fat tissue already know from the very beginning what sort of fat tissue they will be.

Humans and other mammals have two sorts of fatty tissue ¬- white and brown. The white fat tissue is what is usually regarded as 'fat,' the kind many people feel they have too much of. The brown tissue, on the other hand, is a fatty tissue whose job is to burn fat, so that the energy is converted to heat either to keep us (as newborns) warm, or to balance an excessive energy intake.

"This is an answer to many years of discussion in the field, where two views have been put forward: that the cells can have two different fates, brown or white, or that they were predetermined to be one or the other, as this study now shows. An additional and highly unexpected finding was that it could be demonstrated that the very young cells that were to become brown fat cells had characteristics similar to those of young muscle cells," says Barbara Cannon, professor of physiology at the Wenner-Gren Institute, Stockholm University.

The discovery explains to some extent the property that primarily distinguishes brown fat from white fat, namely, its ability to use energy, which is something a muscle cell does in order to work.

... more about:
»Cannon »HDL-cholesterol »Wenner-Gren

Since there is an interest in being able to make use of the potential of brown fat to burn fat and thereby to perhaps help make fat people slim or primarily to counteract the development of obesity in the first place, this discovery is not only of significance in terms of our basic understanding of cell development.

"Our findings do not exclude the possibility of influencing young cells to develop in one direction or the other. It also seems as if there are dormant brown fat cells within the body that could be stimulated to develop and become active, fat-burning cells. Normally adult humans are seen as having rather little brown fat tissue, but new studies using new technologies are starting to challenge this view. We see new potential for understanding the mechanisms that make cells develop into different tissues. And new knowledge always paves the way for new possibilities," says Barbara Cannon.

For further information:
Barbara Cannon, professor of physiology, Wenner-Gren Institute, phone: +46 (0)8-16 4120; cell phone: +46 (0)70-750 0198; e-mail: barbara.cannon@wgi.su.se
Jan Nedergaard, professor of physiology, Wenner-Gren Institute, phone: +46 (0)8-16 4128; cell phone: +46 (0)70-4948955; e-mail: jan@metabol.su.se

James A. Timmons, professor of exercise biology, Heriot Watt University, phone: +44 (0)131 451 4193; cell phone: +44 (0)7833992862; e-mail: J.Timmons@hw.ac.uk

Maria Sandqvist | idw
Further information:
http://www.vr.se

Further reports about: Cannon HDL-cholesterol Wenner-Gren

More articles from Life Sciences:

nachricht 'Y' a protein unicorn might matter in glaucoma
23.10.2017 | Georgia Institute of Technology

nachricht Microfluidics probe 'cholesterol' of the oil industry
23.10.2017 | Rice University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Salmonella as a tumour medication

HZI researchers developed a bacterial strain that can be used in cancer therapy

Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

3rd Symposium on Driving Simulation

23.10.2017 | Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

 
Latest News

Microfluidics probe 'cholesterol' of the oil industry

23.10.2017 | Life Sciences

Gamma rays will reach beyond the limits of light

23.10.2017 | Physics and Astronomy

The end of pneumonia? New vaccine offers hope

23.10.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>