Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pigs arrived in biosecure facility

26.02.2007
Milestone in finding the cure for diabetes

For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.

Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. Insulin-producing islet cells from such high-health pigs are needed to meet the demands in the diabetes community that cannot be realized by using transplantation of human islets.

This facility was funded by a $6.2 million grant from the Diabetes Research & Wellness Foundation's (DRWF), a Washington, D.C. based nonprofit worldwide network dedicated to finding and funding the cure for diabetes. Ryan Companies, U.S., constructed the DRWF Islet Resource Facility.

... more about:
»Diabetes »Facility »high-health »islet »transplants

The 21,000 square-foot bio-secure building will be home to approximately 100 high-health, 'medical-grade' pigs. Pancreatic islet cells from those pathogen-free pigs will be used for transplantation into diabetes patients in clinical trials. There are very few buildings of this kind in the world.

"We had a favorable response from the FDA on the design and operations of this building," said Dr. Henk-Jan Schuurman, CEO of Spring Point Project. "Now, our goal is to be ready for clinical trials within three years, and to provide an FDA-approved standard treatment soon thereafter. We are very pleased that the first animals in the facility meet the high-health standards."

"Populating the Islet Resource Facility marks a major milestone in our ability to offer islet transplants to all patients with diabetes who meet medical criteria," said Dr. Bernhard Hering, a world-renowned diabetes expert and Scientific Director of the Diabetes Institute for Immunology & Transplantation at the University of Minnesota, which may run pre-clinical and clinical trials with Spring Point Project. "Human islet cell transplants have reversed diabetes in 90 percent of our recipients. However, the shortage of human donor organs greatly limits the applicability of islet transplants. Pig islets will solve this demand issue and are at the forefront of a far-reaching cure for patients with diabetes."

The demand for high-health pig islets has been significantly heightened since Dr. Hering and his team last March documented their medical milestone in the prestigious scientific journal Nature Medicine – pig islet cell transplantation yielding long-term diabetes reversal in monkeys, opening the path to unprecedented new opportunities for patients with diabetes.

"This is the reason Spring Point Project was established," said Tom Cartier, president and chairman on the board of Spring Point Project. "The Diabetes Research & Wellness Foundation was among the first to come on board to support our activities. We also appreciate the Juvenile Diabetes Research Foundation for their substantial support of the research team at the University of Minnesota Diabetes Institute for Immunology and Transplantation. We're moving closer to a cure for diabetes as a result of everyone's efforts."

An experienced team at Spring Point Project under leadership of Dr. Schuurman, and working with geneticist Dr. Scott Fahrenkrug of the University of Minnesota, is overseeing the breeding of the animals for safety and high islet production in the facility.

The Hutterian Brethren, a religious farming community in South Dakota, is contributing its expertise with the overseeing and care of the animals.

"The focused efforts in an unique partnership combining top-class expertise in all disciplines needed is the best safeguard for success and based DRWF's decision for funding," commented W. Michael Gretschel, volunteer president of the Diabetes Research & Wellness Foundation. "We will provide the world new hope for transplants that will relieve patients from the day-to-day burdens of insulin administration and threats of high and low blood sugars that cause deadly complications—from blindness to heart attacks, strokes and kidney failure."

henk schuurman | EurekAlert!
Further information:
http://www.springpointproject.org

Further reports about: Diabetes Facility high-health islet transplants

More articles from Life Sciences:

nachricht Complementing conventional antibiotics
24.05.2018 | Goethe-Universität Frankfurt am Main

nachricht Building a brain, cell by cell: Researchers make a mini neuron network (of two)
23.05.2018 | Institute of Industrial Science, The University of Tokyo

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

When corals eat plastics

24.05.2018 | Ecology, The Environment and Conservation

Surgery involving ultrasound energy found to treat high blood pressure

24.05.2018 | Medical Engineering

First chip-scale broadband optical system that can sense molecules in the mid-IR

24.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>