Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pigs arrived in biosecure facility

26.02.2007
Milestone in finding the cure for diabetes

For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.

Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. Insulin-producing islet cells from such high-health pigs are needed to meet the demands in the diabetes community that cannot be realized by using transplantation of human islets.

This facility was funded by a $6.2 million grant from the Diabetes Research & Wellness Foundation's (DRWF), a Washington, D.C. based nonprofit worldwide network dedicated to finding and funding the cure for diabetes. Ryan Companies, U.S., constructed the DRWF Islet Resource Facility.

... more about:
»Diabetes »Facility »high-health »islet »transplants

The 21,000 square-foot bio-secure building will be home to approximately 100 high-health, 'medical-grade' pigs. Pancreatic islet cells from those pathogen-free pigs will be used for transplantation into diabetes patients in clinical trials. There are very few buildings of this kind in the world.

"We had a favorable response from the FDA on the design and operations of this building," said Dr. Henk-Jan Schuurman, CEO of Spring Point Project. "Now, our goal is to be ready for clinical trials within three years, and to provide an FDA-approved standard treatment soon thereafter. We are very pleased that the first animals in the facility meet the high-health standards."

"Populating the Islet Resource Facility marks a major milestone in our ability to offer islet transplants to all patients with diabetes who meet medical criteria," said Dr. Bernhard Hering, a world-renowned diabetes expert and Scientific Director of the Diabetes Institute for Immunology & Transplantation at the University of Minnesota, which may run pre-clinical and clinical trials with Spring Point Project. "Human islet cell transplants have reversed diabetes in 90 percent of our recipients. However, the shortage of human donor organs greatly limits the applicability of islet transplants. Pig islets will solve this demand issue and are at the forefront of a far-reaching cure for patients with diabetes."

The demand for high-health pig islets has been significantly heightened since Dr. Hering and his team last March documented their medical milestone in the prestigious scientific journal Nature Medicine – pig islet cell transplantation yielding long-term diabetes reversal in monkeys, opening the path to unprecedented new opportunities for patients with diabetes.

"This is the reason Spring Point Project was established," said Tom Cartier, president and chairman on the board of Spring Point Project. "The Diabetes Research & Wellness Foundation was among the first to come on board to support our activities. We also appreciate the Juvenile Diabetes Research Foundation for their substantial support of the research team at the University of Minnesota Diabetes Institute for Immunology and Transplantation. We're moving closer to a cure for diabetes as a result of everyone's efforts."

An experienced team at Spring Point Project under leadership of Dr. Schuurman, and working with geneticist Dr. Scott Fahrenkrug of the University of Minnesota, is overseeing the breeding of the animals for safety and high islet production in the facility.

The Hutterian Brethren, a religious farming community in South Dakota, is contributing its expertise with the overseeing and care of the animals.

"The focused efforts in an unique partnership combining top-class expertise in all disciplines needed is the best safeguard for success and based DRWF's decision for funding," commented W. Michael Gretschel, volunteer president of the Diabetes Research & Wellness Foundation. "We will provide the world new hope for transplants that will relieve patients from the day-to-day burdens of insulin administration and threats of high and low blood sugars that cause deadly complications—from blindness to heart attacks, strokes and kidney failure."

henk schuurman | EurekAlert!
Further information:
http://www.springpointproject.org

Further reports about: Diabetes Facility high-health islet transplants

More articles from Life Sciences:

nachricht When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short
23.03.2017 | Institut für Pflanzenbiochemie

nachricht WPI team grows heart tissue on spinach leaves
23.03.2017 | Worcester Polytechnic Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>