Alternative yeast joins genome party.
Budding yeast Saccharomyces cerevisiae makes way for a new genome star.
First there was budding yeast (Saccharomyces cerevisiae). Partly responsible for scientists survival by fermenting their staples beer and bread, they polished off its DNA sequence back in 1997.
Now the minority fungus of lab culture - fission yeast (Schizosaccharomyces pombe) - is fighting back. This week S. pombe enters the experimental big leagues, with the announcement of its completed genome1.
Quality over quantity
S. pombes genome highlights the dissimilarity between the two yeasts. S. pombe has 4,824 genes - about 1,000 less than its cousin, and fewer even than some bacteria. This is evidence of quality over quantity, says Nurse, who led the sequencing effort.
Despite the yeasts differences, "its what they share thats important", says Nurse. He hopes that comparing the two genomes will reveal exactly which parts are essential for yeast life.
Nurses team has already compared the S. pombe genome to another five completed ones - those of budding yeast, the nematode worm Caenorhabditis elegans, the fruit fly (Drosophila), mustard weed (Arabidopsis thaliana) and humans - to find commonalities. All six organisms are eukaryotes - unlike bacteria, they package up their DNA and protein production into distinct compartments within the cell. The team identified a toolkit of some 60 genes that are essential for organizing and dividing eukaryotic cells.
Armed with the genome, S. pombe researchers hope to wade into its proteome, identifying all its proteins and how they interact. But once again, theyre playing catch-up - budding-yeast researchers are well on their way towards this goal.
Still, S. pombe scientists are used to struggling for recognition. And, despite a slow start and early rivalry, "no one would argue for only one yeast now", says Russell.
Scientists still harking after S. cervisiaes brewing power may be won over by S. pombes potential. First described by Swiss researcher Lindner in 1893, he isolated it from East African millet beer - and named it after the Swahili word for beer, pombe.
HELEN PEARSON | © Nature News Service
The interactome of infected neural cells reveals new therapeutic targets for Zika
23.01.2017 | D'Or Institute for Research and Education
Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Life Sciences
23.01.2017 | Materials Sciences
20.01.2017 | Awards Funding