Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Stem cells – The key element for future transplantology

22.01.2007
Stem cell technology hides many of life’s secrets; in scientific terms its application seems boundless.

Research in the field of cellular technologies can lead to a new understanding of the development and differentiation of cells: their ability to transform into various types of cells and fabrics. In case of illness or wound stem cells can be used to restore or replace damaged fabric.

However, to achieve successful results of transplantation and treatment of such significant diseases as Parkinson's disease, Alzheimer's disease, leukemia, diabetes, stroke, muscular dystrophy, hepatic and renal failure etc., optimum methods have to be developed to obtain stem cells and their cultivation. Such a problem is successfully solved by scientists from Kazakhstan - employees of the Research-and-production enterprise "Antigen" under the direction of Project Manager Kaulambaeva Marzhan Zakanovna, head of the "Celluar cultures and culture medium” department. The research is supported actively by the International Science and Technology Center.

The final goal of the project is the creation of a hemopoietic stem cell bank collated from the marrow of an adult and the blood of newborn babies’ umbilical cords. Such a bank has a number of advantages compared with a bank of umbilical cord blood of newborn children and a bank of possible marrow donors. "First of all, during cell cultivation in vitro the concentration of the stem cells in the transplantant increases, thus increasing its biological value,” says Project Manager and Candidate of Biology Kaulambaeva Marzhan Zakanovna. “Secondly, during stem cell cultivation their antigenic properties decrease. Thus the degree of compatibility of donor stem cells and recipients increase, allowing us to avoid graft rejection by the organism, a frequent problem in the bone marrow transplantation of an adult. Thirdly, possessing a sample of stem cells, it is possible to easily restore and, upon subsequent cultivation to accumulate their reserve, if required for a constantly "a renewed material".

... more about:
»cultivation »marrow »stem cells »umbilical

The unique opportunity to collect samples of cells from the various ethnic minorities living within Kazakhstan, undoubtedly raises the value of such a stem cell bank, and, if necessary, it will be possible to deliver cells in any country of the world at the request of any marrow transplantation center.

The project consists of three basic stages. At the initial stage we gather umbilical cord blood. It is established, that if the period of time from the moment of birth to the separation of a newborn child from the placenta is no more than 30 seconds the collected volume of blood, on average, is 25-40ml more than at later separation. The early separation of the child from the placenta has no negative consequences for the newborn. Containers for gathering blood are filled with special preservatives and anticoagulants. The second stage involves checking samples for sterility, in other words checking for the presence of microorganisms or viruses with the application of various nutrient mediums and the polymer chain reaction method. At the final stage cryoconservation of stem cells is performed for long-term storage. During cryoconservation optimum conditions will be developed for long-term storage of stem cells of marrow and blood of newborn children’s umbilical cords with the application of various concentrations of cryoprotectors.

Successful realization of each stage is the guarantee of successfully obtaining stem cells, their cultivation, and their subsequent application, and the developed techniques will be able to successfully combat diseases that are currently considered incurable.

Olga Radkevich | alfa
Further information:
http://tech-db.istc.ru/istc/sc.nsf/events/stem-cells

Further reports about: cultivation marrow stem cells umbilical

More articles from Life Sciences:

nachricht Researchers identify how bacterium survives in oxygen-poor environments
22.11.2017 | Columbia University

nachricht Researchers discover specific tumor environment that triggers cells to metastasize
22.11.2017 | University of California - San Diego

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

UCLA engineers use deep learning to reconstruct holograms and improve optical microscopy

22.11.2017 | Medical Engineering

Watching atoms move in hybrid perovskite crystals reveals clues to improving solar cells

22.11.2017 | Materials Sciences

New study points the way to therapy for rare cancer that targets the young

22.11.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>