Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Stem cells – The key element for future transplantology

22.01.2007
Stem cell technology hides many of life’s secrets; in scientific terms its application seems boundless.

Research in the field of cellular technologies can lead to a new understanding of the development and differentiation of cells: their ability to transform into various types of cells and fabrics. In case of illness or wound stem cells can be used to restore or replace damaged fabric.

However, to achieve successful results of transplantation and treatment of such significant diseases as Parkinson's disease, Alzheimer's disease, leukemia, diabetes, stroke, muscular dystrophy, hepatic and renal failure etc., optimum methods have to be developed to obtain stem cells and their cultivation. Such a problem is successfully solved by scientists from Kazakhstan - employees of the Research-and-production enterprise "Antigen" under the direction of Project Manager Kaulambaeva Marzhan Zakanovna, head of the "Celluar cultures and culture medium” department. The research is supported actively by the International Science and Technology Center.

The final goal of the project is the creation of a hemopoietic stem cell bank collated from the marrow of an adult and the blood of newborn babies’ umbilical cords. Such a bank has a number of advantages compared with a bank of umbilical cord blood of newborn children and a bank of possible marrow donors. "First of all, during cell cultivation in vitro the concentration of the stem cells in the transplantant increases, thus increasing its biological value,” says Project Manager and Candidate of Biology Kaulambaeva Marzhan Zakanovna. “Secondly, during stem cell cultivation their antigenic properties decrease. Thus the degree of compatibility of donor stem cells and recipients increase, allowing us to avoid graft rejection by the organism, a frequent problem in the bone marrow transplantation of an adult. Thirdly, possessing a sample of stem cells, it is possible to easily restore and, upon subsequent cultivation to accumulate their reserve, if required for a constantly "a renewed material".

... more about:
»cultivation »marrow »stem cells »umbilical

The unique opportunity to collect samples of cells from the various ethnic minorities living within Kazakhstan, undoubtedly raises the value of such a stem cell bank, and, if necessary, it will be possible to deliver cells in any country of the world at the request of any marrow transplantation center.

The project consists of three basic stages. At the initial stage we gather umbilical cord blood. It is established, that if the period of time from the moment of birth to the separation of a newborn child from the placenta is no more than 30 seconds the collected volume of blood, on average, is 25-40ml more than at later separation. The early separation of the child from the placenta has no negative consequences for the newborn. Containers for gathering blood are filled with special preservatives and anticoagulants. The second stage involves checking samples for sterility, in other words checking for the presence of microorganisms or viruses with the application of various nutrient mediums and the polymer chain reaction method. At the final stage cryoconservation of stem cells is performed for long-term storage. During cryoconservation optimum conditions will be developed for long-term storage of stem cells of marrow and blood of newborn children’s umbilical cords with the application of various concentrations of cryoprotectors.

Successful realization of each stage is the guarantee of successfully obtaining stem cells, their cultivation, and their subsequent application, and the developed techniques will be able to successfully combat diseases that are currently considered incurable.

Olga Radkevich | alfa
Further information:
http://tech-db.istc.ru/istc/sc.nsf/events/stem-cells

Further reports about: cultivation marrow stem cells umbilical

More articles from Life Sciences:

nachricht Immune Defense Without Collateral Damage
23.01.2017 | Universität Basel

nachricht The interactome of infected neural cells reveals new therapeutic targets for Zika
23.01.2017 | D'Or Institute for Research and Education

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Tracking movement of immune cells identifies key first steps in inflammatory arthritis

23.01.2017 | Health and Medicine

Electrocatalysis can advance green transition

23.01.2017 | Physics and Astronomy

New technology for mass-production of complex molded composite components

23.01.2017 | Process Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>