Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers from the CIMA of the University of Navarra have discovered a possible cause of thrombosis

16.01.2007
A team of researchers from the CIMA of the University of Navarra has discovered a possible cause of thrombosis, and has developed a new diagnostic test for this disease.

The scientific project was undertaken in the Hemostasis and Thrombosis Laboratory. Based on this advance, Digna Biotech, the biotechnology firm that develops the patents obtained by the CIMA, has signed an agreement with the pharmaceutical firm Ferrer Internacional. This alliance will permit the commercialization, perhaps this year, of the new diagnostic test.

Thrombosis is a disease provoked by the appearance of a thrombus or blood clot, which totally or partially blocks the flow of blood. This pathology constitutes one of the principal causes of death. The researchers from the area of Cardiovascular Sciences of the CIMA base the new diagnostic test on the detection of EPCR antibodies, a substance that protects the blood vessels against obstruction by a thrombus.

Useful for young women suffering heart attack or multiple miscarriages

... more about:
»CIMA »Navarra »thrombosis

At the moment, this diagnostic test may be useful in the treatment of young women who have suffered a myocardial infarction or who have suffered multiple miscarriages due to thrombosis in the placenta. Research is continuing concerning other pathologies, where the biological basis of the disease is thrombosis, such as strokes and pulmonary embolisms. In the future, the new test may serve to design more effective antithrombotic treatments.

The project’s scientists explained that the C protein system constitutes one of the principal mechanisms for avoiding thrombosis in humans, and that the presence of the endothelial protein receptor C (EPCR) is necessary for its correct functioning. The researchers from the CIMA of the University of Navarra have demonstrated the existence of anti-EPCR autoantibodies which impede the antithrombotic function of this system. In addition, they have demonstrated that elevated levels of anti-EPCR antibodies in the serum and plasma of the patients is related to an increased risk of suffering new thrombotic phenomena.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1149

Further reports about: CIMA Navarra thrombosis

More articles from Life Sciences:

nachricht Cryo-electron microscopy achieves unprecedented resolution using new computational methods
24.03.2017 | DOE/Lawrence Berkeley National Laboratory

nachricht How cheetahs stay fit and healthy
24.03.2017 | Forschungsverbund Berlin e.V.

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>