Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

The Babraham Institute co-ordinates new European Infrastructure in Proteomics

05.01.2007
The Babraham Institute is the co-ordinating partner for a new European Research Infrastructure, ‘ProteomeBinders’, which aims to understand how the human genome functions by studying its proteins.

The project, funded through the European Commission’s 6th Framework Programme, sets the stage for an open-access resource of binding molecules directed against the entire human proteome, the full set of over 100,000 proteins specified by the human genome.

Established with initial funding of €1.8 M over 4 years, ‘ProteomeBinders’ is co-ordinated by Dr Mike Taussig, Head of the Technology Research Group at the Babraham Institute, and brings together 26 European partners from 12 countries, and two from the USA.

A major challenge of the post-genomic era is to understand how the information encoded within the genome, and expressed as the proteome, choreographs the biological organisation of cells, tissues and organisms. “This requires a comprehensive, standardised collection of specific protein-binding molecules. ‘ProteomeBinders’ aims to provide the tools required to detect and characterise all the relevant human proteins in tissues and fluids in health and disease,” commented Mike Taussig. Currently, antibodies are the most widely used protein-binders, but novel binder types based on alternative protein scaffolds, nucleic acids, peptides and chemical entities each have significant advantages and will be evaluated through this collaboration.

... more about:
»Infrastructure »Protein »Taussig

Currently there is no pan-European platform for the systematic development and quality control for these essential reagents. The ‘ProteomeBinders’ consortium will coordinate a new European resource, by integrating existing infrastructures, reviewing technologies and high-throughput production methods, standardising tools and applications, and establishing a database.

As one of the largest genome-scale projects in Europe, aiming ultimately to produce and collect hundreds of thousands of specific binders, this resource brings benefits to basic and applied research. The resource will impact on healthcare, diagnostics, target discovery for drug intervention and therapeutics, and will consequently deliver advantages to the research, medical and biotechnology communities.

Contact details:
Dr Claire Cockcroft
Deputy, Corporate Affairs
Email: Claire.Cockcroft@bbsrc.ac.uk
Tel: +44 (0)1223 496260
Fax: +44 (0)1223 496002
Mobile: +44 (0)7786 335978
Dr Mike Taussig (mike.taussig@bbsrc.ac.uk)
Oda Stoevesandt (oda.stoevesandt@bbsrc.ac.uk)

Claire Cockcroft | alfa
Further information:
http://www.proteomebinders.org
http://www.babraham.ac.uk

Further reports about: Infrastructure Protein Taussig

More articles from Life Sciences:

nachricht Research team of the HAW Hamburg reanimated ancestral microbe from the depth of the earth
01.03.2017 | Hochschule für Angewandte Wissenschaften Hamburg

nachricht Researchers Imitate Molecular Crowding in Cells
01.03.2017 | Universität Basel

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

Im Focus: Safe glide at total engine failure with ELA-inside

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

A better way to measure the stiffness of cancer cells

01.03.2017 | Health and Medicine

Exploring the mysteries of supercooled water

01.03.2017 | Physics and Astronomy

Research team of the HAW Hamburg reanimated ancestral microbe from the depth of the earth

01.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>