Involvement of the amygdala in systemic lupus erythematosus
In a paper published in PLoS Medicine from Leiden University Medical Center of 37 patients with neuropsychiatric SLE, 21 patients with SLE, and a group of 12 healthy control participants, damage was found in the amygdala of patients with SLE, especially in patients with anti-NMDA receptor antibodies.
These results offer a glimpse into the interaction between the immune system and the brain.
A related perspective article by Betty Diamond and Bruce Volpe discusses the findings further.
Citation: Emmer BJ, van der Grond G, Steup-Beekman GM, Huizinga TWJ, van Buchem MA (2006) Selective involvement of the amygdala in systemic lupus erythematosus. PLoS Med 3(12): e499.
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