The program, in which a woman's ovary is removed and frozen for possible future use, is being led by Teresa Woodruff, Ph.D., associate director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and executive director of the Institute for Women's Health Research at Northwestern's Feinberg School of Medicine. The long-term goal of the program is to be able to extract and mature eggs from cryopreserved (frozen) ovarian tissues to initiate pregnancies once cancer treatment has been completed.
"This breakthrough may permit not only the potential preservation of fertility options for women and girls with cancer, but also can be applied to normal in vitro fertilization patients. This procedure, when developed, could radically change the way infertility is viewed, reduce and eliminate embryo storage and provide better options for women who do not respond to hormonal therapy, " said Woodruff.
In recognition of the Cancer Center's commitment to providing fertility options to women and men with cancer, it has been recognized as a Fertile Hope Center of Excellence, the fifth medical center in the country to receive this designation. Fertile Hope is a non-profit organization that assists cancer patients faced with infertility.
Woodruff's research involves developing new techniques for the long- term preservation of human ovarian tissue. Scientists are exploring ways to remove immature eggs from this tissue and to mature them in the laboratory so that they can potentially be fertilized at a later date.
At this time, the only pregnancies resulting from this research are in mice. Eligible participants will have one ovary surgically removed at Northwestern Memorial Hospital in an outpatient procedure called a laparoscopy before starting cancer treatment. Eighty percent of the ovary will be preserved for the patient's future use and 20 percent will be used by researchers to explore ways to extract and develop immature eggs.
Scientists and physicians from Northwestern are developing a new discipline described as oncofertility and are organizing a collaboration of national experts that include biophysicists, biomaterials biologists, clinical oncologists, reproductive biologists, psychologists, ethicists and legal scholars. The objectives of oncofertility are to better understand the impact of cancer treatment on fertility, to identify new technologies to preserve fertility and to explore the psychosocial role fertility has on survivorship.
Marla Paul | EurekAlert!
Molecular microscopy illuminates molecular motor motion
26.07.2017 | Penn State
New virus discovered in migratory bird in Rio Grande do Sul, Brazil
26.07.2017 | Fundação de Amparo à Pesquisa do Estado de São Paulo
Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...
Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
26.07.2017 | Event News
21.07.2017 | Event News
19.07.2017 | Event News
26.07.2017 | Physics and Astronomy
26.07.2017 | Life Sciences
26.07.2017 | Earth Sciences