Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cell Therapy in Diabetes

16.11.2006
The European JDRF Center for Beta Cell Therapy in Diabetes reports in the Proceedings of the National Academy of Sciences of the USA its results on cell transplantation in 22 patients with type 1 diabetes.

These patients had a history of failing insulin production since several years making them dependent on insulin injections; their blood glucose levels had remained difficult to control leading to diverse complications including episodes of hypoglycemia with risk for coma.

The Center’s study indicates the number of donor insulin-producing beta cells that need to be transplanted in order to restore the endogenous insulin production and stop the insulin injections, and to control blood sugar levels and avoid hypoglycemia. One year after transplantation, the injection-free recipients produce considerable amounts of insulin with a maximal capacity that represents one fourth of that in age-matched individuals without diabetes.

These data form a basis for cell therapy in diabetes. They serve as reference for subsequent work that optimizes the combination of beta cell therapy and immune modulating drugs. The goal is to reach a long-term metabolic normalization with minimal side effects of the treatment. The biologic characteristics of the successful grafts are also used as quality control criteria in the Center’s projects on large scale laboratory generation of insulin-producing cells, for example from stem cells.

... more about:
»Insulin »beta »insulin-producing

The JDRF Center for Beta Cell Therapy in Diabetes is an international consortium of basic and clinical departments that is led by professor Daniel Pipeleers of Brussels Free University-VUB. The objective of the Center is to develop strategies for prevention and treatment of diabetes. Its program specifically focuses on the protection, replacement and regeneration of the insulin-producing beta cells (info on www.betacelltherapy.org). The Center is supported by the Juvenile Diabetes Research Foundation (New York- www.jdrf.org) and by the 6th Framework Program of the European Union.

Jan Van Autreve | alfa
Further information:
http://www.betacelltherapy.org

Further reports about: Insulin beta insulin-producing

More articles from Life Sciences:

nachricht Building a brain, cell by cell: Researchers make a mini neuron network (of two)
23.05.2018 | Institute of Industrial Science, The University of Tokyo

nachricht Research reveals how order first appears in liquid crystals
23.05.2018 | Brown University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>