Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cell Therapy in Diabetes

16.11.2006
The European JDRF Center for Beta Cell Therapy in Diabetes reports in the Proceedings of the National Academy of Sciences of the USA its results on cell transplantation in 22 patients with type 1 diabetes.

These patients had a history of failing insulin production since several years making them dependent on insulin injections; their blood glucose levels had remained difficult to control leading to diverse complications including episodes of hypoglycemia with risk for coma.

The Center’s study indicates the number of donor insulin-producing beta cells that need to be transplanted in order to restore the endogenous insulin production and stop the insulin injections, and to control blood sugar levels and avoid hypoglycemia. One year after transplantation, the injection-free recipients produce considerable amounts of insulin with a maximal capacity that represents one fourth of that in age-matched individuals without diabetes.

These data form a basis for cell therapy in diabetes. They serve as reference for subsequent work that optimizes the combination of beta cell therapy and immune modulating drugs. The goal is to reach a long-term metabolic normalization with minimal side effects of the treatment. The biologic characteristics of the successful grafts are also used as quality control criteria in the Center’s projects on large scale laboratory generation of insulin-producing cells, for example from stem cells.

... more about:
»Insulin »beta »insulin-producing

The JDRF Center for Beta Cell Therapy in Diabetes is an international consortium of basic and clinical departments that is led by professor Daniel Pipeleers of Brussels Free University-VUB. The objective of the Center is to develop strategies for prevention and treatment of diabetes. Its program specifically focuses on the protection, replacement and regeneration of the insulin-producing beta cells (info on www.betacelltherapy.org). The Center is supported by the Juvenile Diabetes Research Foundation (New York- www.jdrf.org) and by the 6th Framework Program of the European Union.

Jan Van Autreve | alfa
Further information:
http://www.betacelltherapy.org

Further reports about: Insulin beta insulin-producing

More articles from Life Sciences:

nachricht A new technique isolates neuronal activity during memory consolidation
22.06.2017 | Spanish National Research Council (CSIC)

nachricht CWRU researchers find a chemical solution to shrink digital data storage
22.06.2017 | Case Western Reserve University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

Im Focus: Optoelectronic Inline Measurement – Accurate to the Nanometer

Germany counts high-precision manufacturing processes among its advantages as a location. It’s not just the aerospace and automotive industries that require almost waste-free, high-precision manufacturing to provide an efficient way of testing the shape and orientation tolerances of products. Since current inline measurement technology not yet provides the required accuracy, the Fraunhofer Institute for Laser Technology ILT is collaborating with four renowned industry partners in the INSPIRE project to develop inline sensors with a new accuracy class. Funded by the German Federal Ministry of Education and Research (BMBF), the project is scheduled to run until the end of 2019.

New Manufacturing Technologies for New Products

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

A new technique isolates neuronal activity during memory consolidation

22.06.2017 | Life Sciences

Plant inspiration could lead to flexible electronics

22.06.2017 | Materials Sciences

A rhodium-based catalyst for making organosilicon using less precious metal

22.06.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>