Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cell Therapy in Diabetes

16.11.2006
The European JDRF Center for Beta Cell Therapy in Diabetes reports in the Proceedings of the National Academy of Sciences of the USA its results on cell transplantation in 22 patients with type 1 diabetes.

These patients had a history of failing insulin production since several years making them dependent on insulin injections; their blood glucose levels had remained difficult to control leading to diverse complications including episodes of hypoglycemia with risk for coma.

The Center’s study indicates the number of donor insulin-producing beta cells that need to be transplanted in order to restore the endogenous insulin production and stop the insulin injections, and to control blood sugar levels and avoid hypoglycemia. One year after transplantation, the injection-free recipients produce considerable amounts of insulin with a maximal capacity that represents one fourth of that in age-matched individuals without diabetes.

These data form a basis for cell therapy in diabetes. They serve as reference for subsequent work that optimizes the combination of beta cell therapy and immune modulating drugs. The goal is to reach a long-term metabolic normalization with minimal side effects of the treatment. The biologic characteristics of the successful grafts are also used as quality control criteria in the Center’s projects on large scale laboratory generation of insulin-producing cells, for example from stem cells.

... more about:
»Insulin »beta »insulin-producing

The JDRF Center for Beta Cell Therapy in Diabetes is an international consortium of basic and clinical departments that is led by professor Daniel Pipeleers of Brussels Free University-VUB. The objective of the Center is to develop strategies for prevention and treatment of diabetes. Its program specifically focuses on the protection, replacement and regeneration of the insulin-producing beta cells (info on www.betacelltherapy.org). The Center is supported by the Juvenile Diabetes Research Foundation (New York- www.jdrf.org) and by the 6th Framework Program of the European Union.

Jan Van Autreve | alfa
Further information:
http://www.betacelltherapy.org

Further reports about: Insulin beta insulin-producing

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>