Combining two separate observations of cells in brain tumours could enable doctors to improve the success rate of radiotherapy. Speaking today (23 January) at the Institute of Physics Simulation and Modelling Applied to Medicine conference in London, chemical engineer Dr Norman Kirkby from the University of Surrey will explain how using the correct time intervals between a sequence of low dose radiotherapy sessions could increase the chance of curing brain cancers that tend to resist treatment.
The work started with the discovery that there is a class of brain cancers (gliomas) that are susceptible to low doses of radiation, but can resist high doses. These cancers can occur in children as well as adults. They are difficult to treat because they do not form solid lumps that can be removed by surgery. Instead they spread in a diffuse manner through the brain.
The question was, would it be possible to find a way of getting the most benefit from giving multiple sessions of low-dose therapy? A team of chemical engineers, cell biologists and clinicians, drawn from the University of Surrey, Addenbrooke’s Hospital in Cambridge and The Gray Cancer Institute at Mount Vernon Hospital in Middlesex, came together to see if they could make some accurate predictions.
Liezel Tipper | alphagalileo
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