Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Hard-wiring the fruit fly's visual system

Both vertebrate and fruit fly have so-called visual maps in the brain that represent the world they see.

These visual maps consist of millions of nerve cell contacts that need to be wired correctly during development in order for the adult animal to see normally. It is generally thought that the complexity of visual maps, like other brain regions, cannot only be genetically programmed but requires activity by neurons or nerve cells in the brain.

In a new study published in the journal Current Biology, Drs. P. Robin Hiesinger, R. Grace Zhai and co-workers in the laboratory of Dr. Hugo Bellen, director of the Program in Developmental Biology at Baylor College of Medicine, found that this neuronal activity is not required for the formation of the visual map in Drosophila melanogaster, the most common form of fruit fly used in laboratories around the world.

"There is a genetic component (to formation of the vertebrate visual system)," said Bellen, who is also a Howard Hughes Medical Institute investigator. "The neurons in vertebrates are born and are genetically programmed to project into a certain brain region. This is followed by a dynamic phase where neuronal activity refines the visual map. In contrast, in flies the system seems to be completely hard-wired and only rely on genetic inputs."

... more about:
»Bellen »Visual »neurons »vertebrate

"The most obvious difference between the insect and vertebrate brain is their size and the number of neurons and connections that need to be made. A possible explanation for the findings is that the fruit fly has many fewer neurons than vertebrates, and the system can therefore just rely on the genetic components in flies," said Bellen.

"In vertebrates, complexity is added because of the challenge of millions of neurons having to make billions of precise connections. You have to work with a gross topological map first, and neuronal activity refines this map later," he said.

The study adds to an ongoing debate about the extent to which brain wiring can be genetically programmed.

"We have to be careful when we interpret these results in light of the complexity of the human brain," said Bellen.

However, he said, "It is astonishing though how only a few thousand genes can program billions of synaptic connections."

Ross Tomlin | EurekAlert!
Further information:

Further reports about: Bellen Visual neurons vertebrate

More articles from Life Sciences:

nachricht Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München

nachricht Second research flight into zero gravity
21.10.2016 | Universität Zürich

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>