The MRC Council has approved a recommendation from its Physiological Systems and Clinical Sciences Board to provide an increased budget of £14.9 million over the five year period April 2007-2012.
The Unit received funding of £7.5 million for the period 2002-2007.
After a rigorous review which involved seeking the opinions of 30 international experts in the field, the MRC Council gave the highest possible 6.0 rating for the Unit's recent work and future proposals.
The Council also approved the appointment of Professor Dario Alessi as Deputy Director of the Unit.
"This major new commitment from the MRC to the Unit in Dundee is a tremendous boost, and recognises the pre-eminence we have achieved in this field worldwide," said Professor Sir Philip Cohen, Director of the MRC Protein Phosphorylation Unit.
"The additional funding will allow us to expand our cutting-edge research programmes - which aim to understand the causes of global diseases such as arthritis, cancer, diabetes, hypertension and Parkinson's - and to use this information to facilitate the development of drugs to treat these conditions in partnership with the six major pharmaceutical companies with whom we collaborate."
When the new positions awarded are filled, the MRC Protein Phosphorylation Unit will have nine Programme Leaders and 115 staff and account for 16% of the on-going research in the College of Life Sciences at Dundee.
Over the past five years some of the highlights of the Unit's research have included the explanation of how a tumour suppressor called LKB1 prevents cancers from forming, the validation of the enzyme PDK1 as a key target for the development of an anti-cancer drug, the discovery of why mutations in an enzyme called WNK1 cause an inherited hypertension syndrome and the identification of new drug targets to treat chronic inflammatory diseases.
The MRC Council also announced that Dr Nick Morrice, Head of Proteomics in the Unit would be promoted from Band 3 to Band 2 and Dr Kei Sakamoto, Head of the Unit's Molecular Physiology Laboratory from Band 4 to Band 3, both effective April 2007.
The Council also gave approval for the Unit to recruit a biologically-focused Programme Leader with significant X-ray crystallographic expertise, a position which has just been advertised.
Roddy Isles | alfa
Ambush in a petri dish
24.11.2017 | Friedrich-Schiller-Universität Jena
Meadows beat out shrubs when it comes to storing carbon
23.11.2017 | Norwegian University of Science and Technology
High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons
The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
24.11.2017 | Physics and Astronomy
24.11.2017 | Health and Medicine
24.11.2017 | Earth Sciences