The MRC Council has approved a recommendation from its Physiological Systems and Clinical Sciences Board to provide an increased budget of £14.9 million over the five year period April 2007-2012.
The Unit received funding of £7.5 million for the period 2002-2007.
After a rigorous review which involved seeking the opinions of 30 international experts in the field, the MRC Council gave the highest possible 6.0 rating for the Unit's recent work and future proposals.
The Council also approved the appointment of Professor Dario Alessi as Deputy Director of the Unit.
"This major new commitment from the MRC to the Unit in Dundee is a tremendous boost, and recognises the pre-eminence we have achieved in this field worldwide," said Professor Sir Philip Cohen, Director of the MRC Protein Phosphorylation Unit.
"The additional funding will allow us to expand our cutting-edge research programmes - which aim to understand the causes of global diseases such as arthritis, cancer, diabetes, hypertension and Parkinson's - and to use this information to facilitate the development of drugs to treat these conditions in partnership with the six major pharmaceutical companies with whom we collaborate."
When the new positions awarded are filled, the MRC Protein Phosphorylation Unit will have nine Programme Leaders and 115 staff and account for 16% of the on-going research in the College of Life Sciences at Dundee.
Over the past five years some of the highlights of the Unit's research have included the explanation of how a tumour suppressor called LKB1 prevents cancers from forming, the validation of the enzyme PDK1 as a key target for the development of an anti-cancer drug, the discovery of why mutations in an enzyme called WNK1 cause an inherited hypertension syndrome and the identification of new drug targets to treat chronic inflammatory diseases.
The MRC Council also announced that Dr Nick Morrice, Head of Proteomics in the Unit would be promoted from Band 3 to Band 2 and Dr Kei Sakamoto, Head of the Unit's Molecular Physiology Laboratory from Band 4 to Band 3, both effective April 2007.
The Council also gave approval for the Unit to recruit a biologically-focused Programme Leader with significant X-ray crystallographic expertise, a position which has just been advertised.
Roddy Isles | alfa
At last, butterflies get a bigger, better evolutionary tree
16.02.2018 | Florida Museum of Natural History
New treatment strategies for chronic kidney disease from the animal kingdom
16.02.2018 | Veterinärmedizinische Universität Wien
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
16.02.2018 | Information Technology
16.02.2018 | Health and Medicine
16.02.2018 | Physics and Astronomy