The HepatoSys multidisciplinary network will investigate signaling pathways, gene regulation mechanisms, cell signaling dynamics and metabolic activity in hepatocytes, the main liver cell type. "HepatoSys will combine simulations of cellular events with experimental data analysis to yield novel insights about the complex biochemical functions of the liver", says Professor Jens Timmer, scientific spokesman for HepatoSys.
Genedata has developed an established computational platform for Systems Biology research comprising Genedata Phylosopher for investigating pathways, and Genedata Expressionist for analysing large volumes of complex molecular data. The platform is currently used by major research groups to enhance drug discovery and development. HepatoSys has licensed this platform to manage research data, and to integrate and analyze transcriptomic, proteomic and metabolomic data.
In addition, Genedata is developing a customised integrated data management solution, based on this platform, for the HepatoSys network. The solution will feature a specialized data management resource to represent dynamic pathway models. This will enable scientists to store and exchange research results, such as mathematical models of cellular signal transduction pathways, together with relevant simulation results. Professor Timmer added, “We are glad to have Genedata as a partner to support our ambitious Systems Biology research projects”.
The Systems Biology approach is growing more widespread in industrial research circles. HepatoSys is pioneering the use of Systems Biology to probe liver function. "Systems Biology provides novel ways to improve the efficiency of the drug discovery processes, including improvements to the assessment of drug efficacy and safety”, says Dr. Othmar Pfannes, CEO of Genedata AG. “We are delighted to support HepatoSys with our computational solutions for investigating this clinically important cell type”.
Ute Heisner | alfa
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30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH
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28.03.2017 | Aarhus University
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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