Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genedata collaborates with HepatoSys Systems Biology Competence Network

11.07.2006
Genedata announces its collaboration with HepatoSys, a consortium of German research centres that aim to understand the physiology and pathophysiology of the human liver using Systems Biology. Together with the consortium’s academic members, Genedata has developed a computational system to analyze molecular processes in mammalian liver cells.

The HepatoSys multidisciplinary network will investigate signaling pathways, gene regulation mechanisms, cell signaling dynamics and metabolic activity in hepatocytes, the main liver cell type. "HepatoSys will combine simulations of cellular events with experimental data analysis to yield novel insights about the complex biochemical functions of the liver", says Professor Jens Timmer, scientific spokesman for HepatoSys.

Genedata has developed an established computational platform for Systems Biology research comprising Genedata Phylosopher for investigating pathways, and Genedata Expressionist for analysing large volumes of complex molecular data. The platform is currently used by major research groups to enhance drug discovery and development. HepatoSys has licensed this platform to manage research data, and to integrate and analyze transcriptomic, proteomic and metabolomic data.

In addition, Genedata is developing a customised integrated data management solution, based on this platform, for the HepatoSys network. The solution will feature a specialized data management resource to represent dynamic pathway models. This will enable scientists to store and exchange research results, such as mathematical models of cellular signal transduction pathways, together with relevant simulation results. Professor Timmer added, “We are glad to have Genedata as a partner to support our ambitious Systems Biology research projects”.

The Systems Biology approach is growing more widespread in industrial research circles. HepatoSys is pioneering the use of Systems Biology to probe liver function. "Systems Biology provides novel ways to improve the efficiency of the drug discovery processes, including improvements to the assessment of drug efficacy and safety”, says Dr. Othmar Pfannes, CEO of Genedata AG. “We are delighted to support HepatoSys with our computational solutions for investigating this clinically important cell type”.

Ute Heisner | alfa
Further information:
http://www.fdm.uni-freiburg.de

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Supersensitive through quantum entanglement

28.06.2017 | Physics and Astronomy

X-ray photoelectron spectroscopy under real ambient pressure conditions

28.06.2017 | Physics and Astronomy

Mice provide insight into genetics of autism spectrum disorders

28.06.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>