Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Dartmouth study finds that arsenic inhibits DNA repair

30.05.2006
Dartmouth researchers, working with scientists at the University of Arizona and at the Department of Natural Resources in Sonora, Mexico, have published a study on the impact of arsenic exposure on DNA damage. They have determined that arsenic in drinking water is associated with a decrease in the body’s ability to repair its DNA.

"This work supports the idea that arsenic in drinking water can promote the carcinogenic effects of other chemicals," says Angeline Andrew, the lead author and a research assistant professor of community and family medicine at Dartmouth Medical School. "This is evidence that it’s more important than ever to keep arsenic out of drinking water."

The study, which was published online on May 10, 2006, in the journal Environmental Health Perspectives, examined the drinking water and measured the arsenic levels in samples of urine and toenails of people who were enrolled in epidemiologic studies in New Hampshire, and in Sonora, Mexico.

Andrew and her colleagues examined the data in conjunction with tissue samples from the study participants to determine the effect of arsenic on DNA repair. To further corroborate their findings, the researchers conducted laboratory studies to examine the effects of arsenic on DNA repair in cultured human cell models.

"The DNA repair machinery normally protects us from DNA-damaging agents, such as those found in cigarette smoke," says Andrew. "The concern is that exposure to drinking water arsenic may exacerbate the harmful effects of smoking or other exposures."

Andrew explains that in regions of the United States where the rock contains higher levels of arsenic, the greater the likelihood that drinking water sources contain some potential adverse levels of the toxin. While the levels of arsenic in municipal water systems are regularly monitored, there is no mandated testing of arsenic levels in private wells. This is of particular concern since the regions where arsenic levels are high are in rural regions, such as New Hampshire, Maine, Michigan and some regions of the Southwest and Rockies. Private wells are common in these areas as primary sources of drinking water.

Sue Knapp | EurekAlert!
Further information:
http://www.Dartmouth.edu

More articles from Life Sciences:

nachricht Scientists spin artificial silk from whey protein
24.01.2017 | Deutsches Elektronen-Synchrotron DESY

nachricht Choreographing the microRNA-target dance
24.01.2017 | UT Southwestern Medical Center

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists spin artificial silk from whey protein

X-ray study throws light on key process for production

A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Breaking the optical bandwidth record of stable pulsed lasers

24.01.2017 | Physics and Astronomy

Choreographing the microRNA-target dance

24.01.2017 | Life Sciences

Spanish scientists create a 3-D bioprinter to print human skin

24.01.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>