A gene that degrades the body’s collagen infrastructure has been shown to make fat cells fatter and expand girth.
Excess fat is stored in white adipose tissue, the primary energy depot in the body, primarily around the midsection. The gene studied by a University of Michigan team acts as a metabolic scissors, cutting through the collagen tissue matrix that holds fat in place, which allows fat cells to expand beneath the belly.
The collaborative research team, headed by researchers Tae-Hwa Chun, Stephen Weiss, and Alan Saltiel at U-M’s Life Sciences Institute (LSI), discovered that the gene membrane-type 1 matrix metalloproteinase (MT1-MMP) shears the collagen meshwork that holds fat cells in place and frees expanding fat cells, allowing their spread and expansion underneath the skin. The study illustrates a relationship between the gene and obesity and metabolism.
Separate brain systems cooperate during learning, study finds
22.02.2018 | Brown University
Maelstroms in the heart
22.02.2018 | Max-Planck-Institut für Dynamik und Selbstorganisation
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
22.02.2018 | Life Sciences
22.02.2018 | Information Technology
22.02.2018 | Health and Medicine