According to the said researcher, this project “is part of the attempt that many laboratories are currently making worldwide to get to know better the biology of stem cells and the conditions in which some of their varieties could be used to treat some diseases”. In this case, scientists are going to study neural stem cells of adult mouse brains which, after being differentiated from neurons in a lab, will be implanted into the damaged cerebral cortex of genetically identical mice.
As Carmen Estrada explained, there is a specific area in the adult rodents’ brain, the subventricular area, where new neurons are massively generated from neural stem cells during the animals’ life. Although this phenomenon does not exist in humans in normal conditions, stem cells have been also detected in that area, with the possibility of generating new neurons under certain circumstances.
With this project, researchers will obtain information about neural stem cells that remain in the brain after birth, and will analyse their properties while they are in lab cultures, as well as after being implanted into the host brain.
Scientists hope to determine the conditions that allow neuron differentiation and to identify potentially useful genes as regulators or markers of such process. Thus, they will determine to what extent the neurons obtained in culture have the typical molecular structure of cells of its phenotype in adult brains.
In short, these trials will allow to establish “whether or not suitable neurons from neural stem cells can be transplanted into the brain of another animal”. The results will allow scientists to get to know the evolution of transplants and provide useful data in order to develop a cellular therapy as part of the treatment of some diseases linked to neuronal death.
Ismael Gaona | alfa
New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg
Stingless bees have their nests protected by soldiers
24.02.2017 | Johannes Gutenberg-Universität Mainz
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News