Although these results are of greatest interest to the relatively small group interested in erythrovirus (parvovirus) research, the ideas discussed are of wider interest because they explore in an imaginative way some fundamental biological events occurring during and after infection.
The research group lead by professor Klaus Hedman at the University of Helsinki have investigated by qualitative and quantitative molecular assays a large number of human tissue samples (birth-year range 1913-2000) and patient sera from the past two decades, for genomic DNA of new and previously known human erythrovirus types. They disclosed in human tissues erythrovirus genome persistence, which is ubiquitous and life-long, and represents a new source of information of our past – which they termed the Bioportfolio.
In the Bioportfolio the researchers observed that in Central and Northern Europe the newly found erythrovirus type 2 in occurrence was actually older than the virus prototype; and that the other recently found type 3 never attained wide circulation in the area during the 70-year observation period from the thirties to the present day. Thereby, the Bioportfolio constitutes at the individual level a new form of "medical record" for one’s infectious encounters. At the global and epidemiological level, it provides a novel database for analysis of the occurrence and circulation of microbial species and their variants.
Furthermore, in light of the previously shown integrity and full-length coding potential of the persistent macromolecular viral DNA genomes, the Bioportfolio might provide the desired long-term permanence for gene therapy vectors, which in the future could be designed in accordance with this innate characteristic of the human body.
Paivi Lehtinen | alfa
The balancing act: An enzyme that links endocytosis to membrane recycling
07.12.2016 | National Centre for Biological Sciences
Transforming plant cells from generalists to specialists
07.12.2016 | Duke University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
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07.12.2016 | Health and Medicine
07.12.2016 | Life Sciences
07.12.2016 | Health and Medicine