This property of silver has caused great interest especially as new resistant strains of bacteria have become a serious problem in public health.
Transmission Electron Microscope (TEM) image of silver nanoparticles produced by the Leicester source with an average diameter of about 15nm (1,000 times smaller than the width of a human hair). The average size of the particles emerging from the machine can be controlled in the range 5nm - 20nm.
For example MRSA bacteria kill 5,000 hospital patients a year in the UK alone and any method of attacking them, not involving normal antibiotics, is becoming increasingly important.
Silver in the form of nanoparticles is even more effective, partly because of the high surface/volume fraction so that a large proportion of silver atoms are in direct contact with their environment. In addition, nanoparticles are sufficiently small to pass through outer cell membranes and enter cells’ inner mechanisms.
A recent medical study showed that only silver nanoparticles with sizes less than 10 nm (1,000 times smaller than the width of a human hair) were able to enter cells and disrupt them. The same study showed that silver nanoparticles are highly toxic to the bacteria that colonise the lungs of cystic fibrosis sufferers often with fatal consequences.
Another study indicated that there may be a role for nanoparticles in the fight against AIDS by showing that silver nanoparticles of the same size attach themselves to structures on the surface of the HIV virus and prevent it from binding to host cells.
Professor of Nanoscience at the University of Leicester, Chris Binns, commented: “Clearly there are important medical treatments using silver nanoparticles and this is just one of the examples of how nanotechnology shows great promise in healthcare.
“One of the problems, however, is in getting assemblies of nanoparticles of the same size into the right environment, for example on the surface of a wound dressing or in a colloidal suspension that can either be turned into an aerosol or injected into the body.
“The medical studies carried out so far acknowledge that in existing commercially available nanoparticle suspensions, only 1% of the material consists of nanoparticles of the right size. The Condensed Matter Physics group in Leicester has many years’ experience in designing and building sources of size-selected metal nanoparticles.
“With support from the “Higher Education Reach –Out to Business and the Community Innovation and Regional Fund” (HIRF) this is now being put to good use to develop a machine specifically to produce nanoparticle assemblies for medical applications. The impressive uniformity of silver nanoparticles produced by the source is illustrated in the figure (available on request) and the design enables the nanoparticles to either be coated onto a solid surface or incorporated into a liquid suspension.”
Trials of the anti-microbial effectiveness of the nanoparticle suspensions will begin shortly.
Alex Jelley | alfa
New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg
Stingless bees have their nests protected by soldiers
24.02.2017 | Johannes Gutenberg-Universität Mainz
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News