This property of silver has caused great interest especially as new resistant strains of bacteria have become a serious problem in public health.
Transmission Electron Microscope (TEM) image of silver nanoparticles produced by the Leicester source with an average diameter of about 15nm (1,000 times smaller than the width of a human hair). The average size of the particles emerging from the machine can be controlled in the range 5nm - 20nm.
For example MRSA bacteria kill 5,000 hospital patients a year in the UK alone and any method of attacking them, not involving normal antibiotics, is becoming increasingly important.
Silver in the form of nanoparticles is even more effective, partly because of the high surface/volume fraction so that a large proportion of silver atoms are in direct contact with their environment. In addition, nanoparticles are sufficiently small to pass through outer cell membranes and enter cells’ inner mechanisms.
A recent medical study showed that only silver nanoparticles with sizes less than 10 nm (1,000 times smaller than the width of a human hair) were able to enter cells and disrupt them. The same study showed that silver nanoparticles are highly toxic to the bacteria that colonise the lungs of cystic fibrosis sufferers often with fatal consequences.
Another study indicated that there may be a role for nanoparticles in the fight against AIDS by showing that silver nanoparticles of the same size attach themselves to structures on the surface of the HIV virus and prevent it from binding to host cells.
Professor of Nanoscience at the University of Leicester, Chris Binns, commented: “Clearly there are important medical treatments using silver nanoparticles and this is just one of the examples of how nanotechnology shows great promise in healthcare.
“One of the problems, however, is in getting assemblies of nanoparticles of the same size into the right environment, for example on the surface of a wound dressing or in a colloidal suspension that can either be turned into an aerosol or injected into the body.
“The medical studies carried out so far acknowledge that in existing commercially available nanoparticle suspensions, only 1% of the material consists of nanoparticles of the right size. The Condensed Matter Physics group in Leicester has many years’ experience in designing and building sources of size-selected metal nanoparticles.
“With support from the “Higher Education Reach –Out to Business and the Community Innovation and Regional Fund” (HIRF) this is now being put to good use to develop a machine specifically to produce nanoparticle assemblies for medical applications. The impressive uniformity of silver nanoparticles produced by the source is illustrated in the figure (available on request) and the design enables the nanoparticles to either be coated onto a solid surface or incorporated into a liquid suspension.”
Trials of the anti-microbial effectiveness of the nanoparticle suspensions will begin shortly.
Alex Jelley | alfa
More genes are active in high-performance maize
19.01.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
How plants see light
19.01.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
19.01.2018 | Materials Sciences
19.01.2018 | Health and Medicine
19.01.2018 | Physics and Astronomy