Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Common properties in the genes implicated in the development of cancer

08.03.2006


Two researchers from the University of Navarra, Javier Novo and José Luis Vizmanos, have performed a bioinformatic study on the genes which have been implicated in the development of cancer. The research project has been described in an article which will be published shortly in Trends in Genetics, one of the five best journals in the area of “Genetics and Inheritance”.



This bioinformatic study has permitted the researchers to identify certain common properties in those genes which are involved in the development of cancer. Dr. Novo explained that “the objective consisted in discovering whether those genes which suffer translocations (breakages) in this disease have any structural or functional characteristics in common”.

Concretely, the research project performed by the two scientists of the Department of Genetics at the University of Navarra has provided, for the first time, clear data which support the hypothesis that the most important mechanisms in the development of tumors are those which generate random breakage.


“When a normal cell becomes tumorous, one of the most important changes that it experiences is that its genome becomes unstable, and breaks in various places,” explained Dr. Novo. Until now, there have been many examples of this kind of breakage published, “but it was not well known what caused them nor how they were produced; for example, if they were produced at random, or if there was something in the sequence which aided in their appearance in concrete locations.”

Database with Genome Regions

The authors of the article published in Trends in Genetics have constructed a data base with all the regions of the genome which break in the various types of tumors. “Over the course of several months, with the help of students from the School of Sciences, we collected from the scientific literature all the breakages which have been described in relation to cancer, we located them in the sequence of the human genome and we studied the characteristics of the regions in which they appear.”

Characterizing the processes which provoke breakage is one of the issues which arouses greatest interest among the scientific community. In addition, according to this researcher, “understanding the mechanisms by which cancer develops could mean a great advance in the struggle against this disease”.

Garazi Andonegi | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=914

More articles from Life Sciences:

nachricht A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>