Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Common properties in the genes implicated in the development of cancer

08.03.2006


Two researchers from the University of Navarra, Javier Novo and José Luis Vizmanos, have performed a bioinformatic study on the genes which have been implicated in the development of cancer. The research project has been described in an article which will be published shortly in Trends in Genetics, one of the five best journals in the area of “Genetics and Inheritance”.



This bioinformatic study has permitted the researchers to identify certain common properties in those genes which are involved in the development of cancer. Dr. Novo explained that “the objective consisted in discovering whether those genes which suffer translocations (breakages) in this disease have any structural or functional characteristics in common”.

Concretely, the research project performed by the two scientists of the Department of Genetics at the University of Navarra has provided, for the first time, clear data which support the hypothesis that the most important mechanisms in the development of tumors are those which generate random breakage.


“When a normal cell becomes tumorous, one of the most important changes that it experiences is that its genome becomes unstable, and breaks in various places,” explained Dr. Novo. Until now, there have been many examples of this kind of breakage published, “but it was not well known what caused them nor how they were produced; for example, if they were produced at random, or if there was something in the sequence which aided in their appearance in concrete locations.”

Database with Genome Regions

The authors of the article published in Trends in Genetics have constructed a data base with all the regions of the genome which break in the various types of tumors. “Over the course of several months, with the help of students from the School of Sciences, we collected from the scientific literature all the breakages which have been described in relation to cancer, we located them in the sequence of the human genome and we studied the characteristics of the regions in which they appear.”

Characterizing the processes which provoke breakage is one of the issues which arouses greatest interest among the scientific community. In addition, according to this researcher, “understanding the mechanisms by which cancer develops could mean a great advance in the struggle against this disease”.

Garazi Andonegi | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=914

More articles from Life Sciences:

nachricht Stiffness matters
22.02.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht Separate brain systems cooperate during learning, study finds
22.02.2018 | Brown University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Stiffness matters

22.02.2018 | Life Sciences

Magnetic field traces gas and dust swirling around supermassive black hole

22.02.2018 | Physics and Astronomy

First evidence of surprising ocean warming around Galápagos corals

22.02.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>