Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


U of MN research shows how infection-fighting cells interact


Researchers at the University of Minnesota have identified key insights into how different types of infection-fighting T-cells survive and co-exist within the body’s immune system.

T-cells, or lymphocytes, are the body’s natural defense mechanism against infection, directly attacking foreign bodies such as bacteria and viruses. The body contains millions of different lymphocytes that fight specific infectious microbes. Research published in the March 3, 2006 issue of Science Express suggests that having a wide variety of each specific T-cell in fewer quantities leads to optimal survival and activity of these infection-fighting cells. Competition within each type of T-cell allows the body to maintain a diverse inventory of natural infection fighters.

"Without this balance, a body’s immune system will not have the desired response when faced with infection," said Marc Jenkins, professor of microbiology at the University of Minnesota and co-author of the study. "These findings could aid the development and production of vaccines and lead to further research on how the body fights specific infections, such as HIV."

Jenkins and his student, Jason Hataye, from the joint M.D./Ph.D. program at the University of Minnesota, developed a method to monitor very small numbers of specific T-cells in mice. Using this system, they found that the cells survived and activated at a significantly higher rate in mice that contained the normal amount of these T-cells, as opposed to those that were intravenously injected with 2,000 times the normal amount of that type of T-cell.

"It’s a needle in the haystack problem. We used a magnet to find the needle," said Hataye. "The ability to monitor the lifespan and survival of one specific cell type will be key to future research and understanding how these cells interact."

Liz Bryan | EurekAlert!
Further information:

More articles from Life Sciences:

nachricht First time-lapse footage of cell activity during limb regeneration
25.10.2016 | eLife

nachricht Phenotype at the push of a button
25.10.2016 | Institut für Pflanzenbiochemie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Greater Range and Longer Lifetime

26.10.2016 | Power and Electrical Engineering

VDI presents International Bionic Award of the Schauenburg Foundation

26.10.2016 | Awards Funding

3-D-printed magnets

26.10.2016 | Power and Electrical Engineering

More VideoLinks >>>