Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

How nice, brown rice: Study shows rice bran lowers blood pressure in rats

03.03.2006


Thousands of years ago, humans began scrubbing off and discarding the outer layer of long-grain rice, preferring the polished white kernel beneath. Now, for the first time, scientists in Japan have shown that this waste product of rice processing, called rice bran, significantly lowers blood pressure in rats whose hypertension resembles that of humans.



The team reports their findings in the March 8 issue of the Journal of Agricultural and Food Chemistry, published by the American Chemical Society, the world’s largest scientific society.

A commonly prescribed class of drugs called ACE inhibitors dilates the arteries of hypertensive patients and thus decreases their risk of stroke, heart attack and kidney disease. But the drugs can also carry side effects: chronic cough, allergic reactions, dizziness, even kidney problems.


What if some component of our diet could work in similar fashion, with few or no side effects? Researchers at Tohoku University and Japan’s National Research Institute of Brewing demonstrated that adding rice bran to the diets of hypertensive, stroke-prone rats lowered the animals’ systolic blood pressure by about 20 percent and, via the same mechanism, inhibited angiotensin-1 converting enzyme, or ACE.

“There’s much work being done on various bran fractions to nail down any health benefits,” says the journal’s editor, James Seiber, Ph.D., who is also director of the U.S. Department of Agriculture’s Western Regional Research Center in Davis, Calif. “This particular paper caught my attention for two reasons: the potential of bringing a waste product like rice bran into beneficial use, and the way the group went about their study with good controlled experiments using an appropriate model.”

It’s still not clear whether simply eating more brown rice, which retains some of its bran, would reduce the risk of heart disease. However, previous research in humans, as well as animals with high cholesterol, does suggest that certain fractions of rice bran can lower levels of unhealthy LDL cholesterol.

The Tohoku study adds antihypertensive activity to the picture, along with a host of other biochemical markers that track blood glucose (implicated in diabetes), lipid profile, kidney function and the harmful effects of free radicals.

For example, high levels of a marker called 8-OHdG indicate biological stress and genetic damage due to oxygen-based free radicals. The researchers found that rice bran, which contains various forms of the antioxidant Vitamin E, markedly lowered the rats’ levels of the peptide 8-OHdG.

“Oxidative stress plays an important role in the initiation and progression of cardiovascular diseases,” explained lead author Ardiansyah [editor note: name is correct as written, there is no first name], a Ph.D. candidate at the university’s School of Agricultural Science.

He added one more element to the research that is new: using enzymes to clip components of rice bran from its cell walls, rather than extracting a fraction with ethanol. “I think enzymatic treatment will be more suitable for applications if we’d like to use [rice bran as] functional food,” he said.

The researchers’ next step is to elucidate the mechanisms by which specific components of rice bran inhibit ACE and lower cholesterol.

Michael Bernstein | EurekAlert!
Further information:
http://www.acs.org

More articles from Life Sciences:

nachricht Researchers uncover protein-based “cancer signature”
05.12.2016 | Universität Basel

nachricht The Nagoya Protocol Creates Disadvantages for Many Countries when Applied to Microorganisms
05.12.2016 | Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

IHP presents the fastest silicon-based transistor in the world

05.12.2016 | Power and Electrical Engineering

InLight study: insights into chemical processes using light

05.12.2016 | Materials Sciences

High-precision magnetic field sensing

05.12.2016 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>