An innovative method of categorizing myosin—one of three molecular “motors” that produce movement within the cells of the body—has dramatically increased the amount of information available about these essential proteins. The studies lay the groundwork for development of treatments for conditions ranging from certain kinds of blindness and kidney disease to neurodegenerative disorders and parasitic diseases such as malaria.
All complex organisms use myosin and its relatives, kinesin and dynein, to move substances around inside cells and to help cells move from one place to the other. Myosins also help parasites enter and infect hosts. Defects in the motors play a role in a variety of human and animal disorders, including retinitis pigmentosa (which causes blindness), polycystic kidney disease, brain development defects, neurodegenerative diseases, muscular dystrophy, skin pigmentation problems, and genetic hearing loss.
Researchers led by Dominique Soldati, a Howard Hughes Medical Institute (HHMI) international research scholar at the University of Geneva in Switzerland, have developed a new system of classifying myosins. Up to now, researchers have only studied approximately 130 myosins at a time. The new system includes 250 myosins and increases the number of myosin subclasses from 18 to 24, enabling researchers to better understand each myosins function.
Cindy Fox Aisen | EurekAlert!
The balancing act: An enzyme that links endocytosis to membrane recycling
07.12.2016 | National Centre for Biological Sciences
Transforming plant cells from generalists to specialists
07.12.2016 | Duke University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
07.12.2016 | Health and Medicine
07.12.2016 | Life Sciences
07.12.2016 | Health and Medicine