The last 20 years research on Assisted Reproductive Technologies (ART), focused almost exclusively on embryos. Despite the impressive technological advances the live birth rate has stalled at between 25% - 27%. The uterus, where the embryo must implant and develops, had been poorly studied. A successful pregnancy is the result of a complex molecular and cellular exchange established between the mother and the embryo since the early stages of pregnancy until baby deliver.
Today, we are able to transfer “good quality embryos” (based solely on morphological characteristics) into the maternal uterus, however, we don’t know if the uterus is ready to receive the embryo. Out of 50% of the ART failure cases are due to the impossibility by the maternal uterus to host the embryo at the moment of the embryo transfer. Also a “non-receptive uterus” can explain why 15% of couples using ART never become parents.
We must then work to understand both the fundamental and clinical aspects of the early pregnancy, and specially the complexity of the molecular and cellular exchanges during the embryo implantation in the maternal uterus. Understanding the EMByo Implantation Control at both embryo and maternal levels is the goal of the EMBIC network of excellence (www.embic.org). This consortium partially financed by the European Commission is composed of more than 200 researchers and clinicians from 18 leading European institutions of 9 countries. A better understanding of this early “molecular conversation” between the mother and the embryo will permit us to propose new therapies and technologies increasing ART success rates.
Juarez Perez Victor | alfa
Cancer diagnosis: no more needles?
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A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
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At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
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There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
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