When cells age and stop dividing, how much do they contribute to whole-body aging? Brown University research strengthens the case for a strong connection by providing evidence that non-dividing or “replicatively senescent” cells can be found in large numbers in old animals. The research, led by John Sedivy, is the first to quantify the presence of these cells in any species. Results are published by Science.
Markers for replicative senescence - The presence of biomarkers, or biological “red flags,” for old, non-dividing cells in baboons increases dramatically with age. This finding, from the lab of Brown biologist John Sedivy, bolsters the theory that replicative aging on a cellular level contributes to aging in whole organisms – including humans.
Brown University biologists have uncovered intriguing evidence to support the theory that old cells help make old bodies. In a study of baboons, scientists showed that as these animals age, the number of aging cells in their skin significantly increases.
Over time, cells lose their ability to divide, a state known as replicative senescence. The new research, published in an advanced online edition of Science, is the first to quantify the presence of replicatively senescent cells in any species.
Wendy Lawton | EurekAlert!
Rochester scientists discover gene controlling genetic recombination rates
23.04.2018 | University of Rochester
One step closer to reality
20.04.2018 | Max-Planck-Institut für Entwicklungsbiologie
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
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12.04.2018 | Event News
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23.04.2018 | Physics and Astronomy
23.04.2018 | Physics and Astronomy
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