Findings may lead to future predictive test for preeclampsia
Mayo Clinic researchers have found an association between abnormally high levels of a protein named HtrA1 and preeclampsia, a sudden and dangerous rise in blood pressure that can result in premature delivery, disability or death for mother and fetus. The condition, which affects 5 to 8 percent of pregnancies worldwide, constitutes a medical emergency and often requires a Caesarean section delivery. The condition is estimated to cause 50,000 to 76,000 maternal deaths each year.
The Mayo Clinic work is the first to link high levels of HtrA1 in third-trimester placental tissues with severe preeclampsia. The results will be reported at the Society for Maternal-Fetal Medicine annual meeting in Miami.
Lisa Lucier | EurekAlert!
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