Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bones from blood: scientists aim to break new ground on fractures

31.01.2006


Scientists at the University of York have launched a new research project which aims to develop ways of making bones from blood.



Researchers from the University’s Department of Biology are heading the EC-backed project to create bone structures from cord blood stem cells for use in the repair of bone defects and fractures.

The three-year €2.5 million research project involves scientists in the UK and across Europe, as well as academics from the University of York’s Departments of Sociology and Philosophy, who will carry out sociological and ethical evaluations of the work. The project will seek to find a viable new medical use for the two million units of cord blood banked in Europe, and currently used for transfusions and treating leukaemia.


Biologist Dr Paul Genever, who is co-ordinating the project, said: “The mesenchymal stem cells (MSCs) in cord blood appear similar to bone marrow stem cells but they are hard to locate. We aim to isolate and expand them so we have enough cells to use in therapies.

“We also want to compare them with bone marrow and embryonic stem cells and investigate how we can turn them into bone structures for use as 3D bone replacements.”

Dr Genever said if the creation of bone structures from stem cells proves viable, it might be used for cell-based therapies to repair bone defects and fractures. Ultimately, bone structures developed in this way could be used to make hip replacements more durable.

“The participation of colleagues from Sociology and Philosophy in a project such as this offers the opportunity for us to explore a more ethically and socially integrated kind of biology,” he added.

Professor Andrew Webster and Dr Nik Brown, of the Science and Technology Studies Unit (SATSU) in the Department of Sociology, will link the scientific questions of MSC isolation and expansion to the wider environment and define potential barriers and areas of weakness in their use. They will consider questions such as safety and standards, commercial viability, potential investment, consensus amongst scientists and clinical distribution.

Dr Stephen Holland and Professor Tom Baldwin, of the Department of Philosophy, will carry out an ethical evaluation of the research. This will include making sure that the project is conducted according to the highest standards of research governance. They will also investigate how the project contributes to the debate about the ethics of stem cell research. In particular, they will consider how potential benefits of these stem cell therapies can be weighed against ethical concerns."

David Garner | alfa
Further information:
http://www.york.ac.uk/admin/presspr/pressreleases/bonesfromblood.htm

More articles from Life Sciences:

nachricht Newly designed molecule binds nitrogen
23.02.2018 | Julius-Maximilians-Universität Würzburg

nachricht Atomic Design by Water
23.02.2018 | Max-Planck-Institut für Eisenforschung GmbH

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Attoseconds break into atomic interior

A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.

In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...

Im Focus: Good vibrations feel the force

A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.

By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Basque researchers turn light upside down

23.02.2018 | Physics and Astronomy

Finnish research group discovers a new immune system regulator

23.02.2018 | Health and Medicine

Attoseconds break into atomic interior

23.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>