The treatment of inflammatory bowel disease, which includes Crohn’s disease and ulcerative colitis, has very high costs and can include admissions and surgical interventions. Until now, there was no precise tools to predict the evolution and prognosis of these diseases. A new biochip, IBDchip, (Inflammatory Bowel Disease DNA Chip) is a pioneering programme which has the aim to have a direct influence in the quality of life of patients.
This chip has been created by the biotechnology enterprise Progenika Biopharma, and IDIBAPS-Hospital Clínic de Barcelona has led the multicentre study which demonstrates the improving of the prognosis and therapeutics applied to patients with inflammatory bowel disease. Dr. Miquel Sans, from the Gastroenterology Department of Hospital Clínic and collaborator of the IDIBAPS group Physiopatology of gastrointestinal lesions has been in charge of the coordination of the trial and has participated, along with Dr. Carlos Cara, of UCB Pharma, in the development of the diagnostic chip.
This study had the participation of 579 patients (335 of which with Crohn’s disease and 344 with ulcerous colitis), and of the Central University Hospital of Asturias, University Clinical Hospital of Santiago de Compostela and Lozano Blesa Clinical Hospital of Zaragoza.
Àlex Argemí Saburit | alfa
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Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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